CAS 172889-27-9: Src kinase inhibitor PP2

Description: Src kinase inhibitor PP2 is a small molecule compound known for its role as a selective inhibitor of Src family kinases, which are involved in various cellular processes, including proliferation, differentiation, and survival. The compound is characterized by its ability to interfere with the ATP-binding site of Src kinases, thereby inhibiting their activity. This inhibition can lead to the modulation of signaling pathways associated with cancer progression and metastasis. PP2 is often utilized in research settings to study the effects of Src inhibition on cellular behavior and to explore potential therapeutic applications in cancer treatment. The compound is typically administered in vitro and has been shown to affect various cellular functions, including migration and invasion. Its chemical structure includes specific functional groups that contribute to its binding affinity and selectivity for Src kinases. As with many kinase inhibitors, the use of PP2 may also be associated with off-target effects, necessitating careful interpretation of experimental results.

Formula: C₁₅H₁₆ClN₅

InChI: InChI=1S/C15H16ClN5/c1-15(2,3)21-14-11(13(17)18-8-19-14)12(20-21)9-4-6-10(16)7-5-9/h4-8H,1-3H3,(H2,17,18,19)

InChI key: InChIKey=PBBRWFOVCUAONR-UHFFFAOYSA-N

SMILES: ClC=1C=CC(=CC1)C2=NN(C=3N=CN=C(N)C23)C(C)(C)C

Synonyms:

• 1-(Tert-Butyl)-3-(4-Chlorophenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
• 1-(Tert-Butyl)-3-(4-Chlorophenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
• 1-tert-Butyl-3-(4-chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-amine
• 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-
• 3-(4-Chlorophenyl) 1-(1,1-Dimethylethyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
• 3-(4-Chlorophenyl)-1-(1,1-dimethylethyl)-(1H)-pyrazolo[3.4-d]pyrimidine-4-amine
• 4-Amino-3-(4-chlorophenyl)-1-(t-butyl)-1H-pyrazolo[3,4-d]pyrimidine
• 4-Amino-5-(4-Chlorophenyl)-7-(T-Butyl)Pyrazolo[3,4-D]Pyrimidine
• 4-Amino-5-(4-Chlorophenyl)-7-(Tert-Butyl)Pyrazolo[3,4-D]Pyrimidine
• Ag 1879
• Agl 1879
• PP 2 (enzyme inhibitor)
• Src kinase inhibitor PP2
• PP 2

PP2

CAS: 172889-27-9

• Formula: C₁₅H₁₆ClN₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 301.774

1-(Tert-Butyl)-3-(4-Chlorophenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine

CAS: 172889-27-9

• Molecular weight: 301.78g/mol

PP2

CAS: 172889-27-9

• Purity: 95.65%
• Molecular weight: 301.77g/mol

PP 2

CAS: 172889-27-9

• Formula: C₁₅H₁₆ClN₅
• Purity: >97.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 301.78

PP2

CAS: 172889-27-9

PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less …

• Formula: C₁₅H₁₆ClN₅
• Purity: 95.65% - 98%
• Color and Shape: White Solid
• Molecular weight: 301.77

PP2

CAS: 172889-27-9

• Formula: C₁₅H₁₆ClN₅
• Molecular weight: 301.8

PP2

CAS: 172889-27-9

Applications PP 2 is a Src kinase inhibitor used in chemotherapy in the induction of …

• Formula: C₁₅H₁₆ClN₅
• Color and Shape: Neat
• Molecular weight: 301.774

PP 2

CAS: 172889-27-9

PP2 is a protein phosphatase inhibitor that binds to and inhibits the activity of protein …

• Formula: C₁₅H₁₆ClN₅
• Purity: Min. 95%
• Molecular weight: 301.78 g/mol