CAS 17341-93-4

2,2,2-Trichloroethyl chloroformate

Description:

2,2,2-Trichloroethyl chloroformate, with the CAS number 17341-93-4, is an organic compound characterized by its chloroformate functional group. This substance is typically a colorless to pale yellow liquid with a pungent odor, indicative of its reactivity and potential hazards. It is known for its use as a reagent in organic synthesis, particularly in the formation of esters and in the protection of alcohols. The presence of three chlorine atoms in its structure contributes to its high reactivity and potential toxicity, making it a compound that requires careful handling and storage. It is soluble in organic solvents but has limited solubility in water. Due to its reactive nature, it can undergo hydrolysis in the presence of moisture, releasing hydrochloric acid and potentially leading to corrosive effects. Safety precautions are essential when working with this compound, as it can be harmful if inhaled, ingested, or in contact with skin. Proper personal protective equipment and fume hoods are recommended during its use in laboratory settings.

Formula: C₃H₂Cl₄O₂

InChI: InChI=1S/C3H2Cl4O2/c4-2(8)9-1-3(5,6)7/h1H2

InChI key: InChIKey=LJCZNYWLQZZIOS-UHFFFAOYSA-N

SMILES: C(C(Cl)(Cl)Cl)OC(Cl)=O

Synonyms:

• (Trichloroethoxy)chloroformate
• 2,2,2-Trichloro-Ethoxycarbonyl Chloride
• 2,2,2-Trichloroethoxycarbonyl chloride
• 2,2,2-Trichloroethyl Carbonochloridate
• 2,2,2-Trichloroethyl Chloroformate
• 2,2,2-Trichloroethyl chloridocarbonate
• Beta,Beta,Beta-Trichloroethoxycarbonyl Chloride
• Carbonochloridic acid, 2,2,2-trichloroethyl ester
• Carbonochloridicacid,2,2,2-Trichloroethylester
• Chloroformic Acid 2,2,2-Trichloroethyl Ester
• Ethanol, 2,2,2-trichloro-, chloroformate
• Formic acid, chloro-, 2,2,2-trichloroethyl ester
• NSC 152038
• Sec-Butyl Chloroformate
• Trichloroethyl chloroformate
• Troc-Cl
• Troc-Cl trichloroethoxycarbonyl chloride
• Z(2-Br)OSU
• β,β,β-Trichloroethoxycarbonyl chloride

2,2,2-Trichloroethyl Chloroformate

CAS: 17341-93-4

Formula: C₃H₂Cl₄O₂

Purity: >98.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 211.85

Ref: 3B-C0795

2,2,2-Trichloroethyl chloroformate

CAS: 17341-93-4

Formula: ClCO₂CH₂CCl₃

Purity: ≥ 98.0%

Color and Shape: Clear, colourless to pale yellow liquid

Molecular weight: 211.86

Ref: 7W-GK2608

2,2,2-Trichloroethyl chloroformate

CAS: 17341-93-4

2,2,2-Trichloroethyl chloroformate

Formula: C₃H₂Cl₄O₂

Purity: 95%

Color and Shape: clear. colourless liquid

Molecular weight: 211.86g/mol

Ref: 54-OR16412

2,2,2-Trichloroethyl Chloroformate

CAS: 17341-93-4

Formula: C₃H₂Cl₄O₂

Molecular weight: 211.85

Ref: 4Z-C-334006

2,2,2-Trichloroethyl chloroformate

CAS: 17341-93-4

Formula: C₃H₂Cl₄O₂

Purity: 97%

Color and Shape: Liquid

Molecular weight: 211.85

Ref: 10-F101886

2,2,2-Trichloroethyl Chloroformate

Controlled Product

CAS: 17341-93-4

Applications 2,2,2-Trichloroethyl Chloroformate is a general reagent for the demethylation of tertiary methylamines. It is used as a reagent in the synthesis of a series of piperazine ureas as fatty acid amide hydrolase inhibitors and analgesics. Also used as a reagent in the synthesis of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Montzka, T.A., et al.: Tetrahedron Lett., 15, 1325 (1974); Kono, M., et al.: Bioorg. Med. Chem., 22, 1468 (2014); Gillespie, P., et al.: Bioorg. Med. Chem. Lett., 24, 949 (2014)

Formula: C₃H₂Cl₄O₂

Color and Shape: Neat

Molecular weight: 211.86

Ref: TR-T774340

2,2,2-Trichloroethylchloroformate

CAS: 17341-93-4

2,2,2-Trichloroethylchloroformate is a chlorinating agent that is used in the synthesis of taxol. It has been shown to be a potent inducer of Toll-like receptor 4 (TLR4). TLR4 is an immune system protein that recognizes bacteria and activates the inflammatory response. 2,2,2-Trichloroethylchloroformate has also been shown to be an effective treatment for bowel disease and can be used as a h1 antagonist. The chemical also has analytical applications in wastewater treatment and infectious diseases. The compound has been found to induce nuclear DNA damage in human serum cells in vitro. 2,2,2-Trichloroethylchloroformate can be synthesized by palladium-catalyzed coupling with chlorogenic acids and its derivatives. This chemical is also able to inhibit the growth of human cancer cells in vitro.

Formula: ClCO₂CH₂CCl₃

Purity: Min. 95%

Color and Shape: Colorless Clear Liquid

Molecular weight: 211.86 g/mol

Ref: 3D-FT16026

2,2,2-Trichloroethyl chloroformate, 97%

CAS: 17341-93-4

2,2,2-Trichloroethyl chloroformate is used as a protecting reagent for aliphatic and aromatic hydroxyl and amino groups. It is used as derivatizing reagent in gas chromatographic/mass spectrometric determination of a large range of amphetamine-related drugs and ephedrines in plasma, urine and hair s

Formula: C₃H₂Cl₄O₂

Purity: 97%

Color and Shape: Clear colorless, Liquid

Molecular weight: 211.85

Ref: 02-L06875

Carbonochloridic acid, 2,2,2-trichloroethyl ester

CAS: 17341-93-4

Formula: C₃H₂Cl₄O₂

Purity: 97%

Color and Shape: Liquid

Molecular weight: 211.8588

Ref: IN-DA001YVE