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CAS 17402-86-7

:

Benzo[b]thiophene, 4-nitro-, 1,1-dioxide

Formula:C8H5NO4S
InChI:InChI=1S/C8H5NO4S/c10-9(11)7-2-1-3-8-6(7)4-5-14(8,12)13/h1-5H
InChI key:LWKOZDAODXAJCF-UHFFFAOYSA-N
SMILES:C1=CC(=C2C=CS(=O)(=O)C2=C1)[N+](=O)[O-]
Synonyms:
  • PHGDH-IN-5
  • PHGDH-IN-5 (Compound B12)
  • Benzo[b]thiophene, 4-nitro-, 1,1-dioxide
Found 1 products.
  • PHGDH-IN-5
    Targetmol
    + Info

    PHGDH-IN-5

    CAS:
    Compound B12 (PHGDH-IN-5) acts as a covalent inhibitor of PHGDH, demonstrating an IC50 value of 0.29 μM. It has been shown to inhibit the proliferation of cancer cell lines that overexpress PHGDH and reduce the production of glucose-derived serine in MDA-MB-468 cells [1].
    Formula:C8H5NO4S
    Color and Shape:Solid
    Molecular weight:211.20

    Ref: TM-T87143