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CAS 17402-86-7

:

Benzo[b]thiophene, 4-nitro-, 1,1-dioxide

Formula:C8H5NO4S
Synonyms:
  • PHGDH-IN-5
  • PHGDH-IN-5 (Compound B12)
  • Benzo[b]thiophene, 4-nitro-, 1,1-dioxide
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  • PHGDH-IN-5
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    PHGDH-IN-5

    CAS:
    Compound B12 (PHGDH-IN-5) acts as a covalent inhibitor of PHGDH, demonstrating an IC50 value of 0.29 μM. It has been shown to inhibit the proliferation of cancer cell lines that overexpress PHGDH and reduce the production of glucose-derived serine in MDA-MB-468 cells [1].
    Formula:C8H5NO4S
    Color and Shape:Solid
    Molecular weight:211.20

    Ref: TM-T87143

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