CAS 174418-82-7

7-Hydroxymitragynine

Description:

7-Hydroxymitragynine is an indole alkaloid derived from the Mitragyna speciosa plant, commonly known as kratom. It is structurally related to mitragynine, another prominent alkaloid found in the same plant. This compound is characterized by its potential analgesic and stimulant properties, which have garnered interest in both traditional medicine and contemporary research. 7-Hydroxymitragynine interacts with opioid receptors in the brain, which may contribute to its pain-relieving effects. However, it also exhibits a complex pharmacological profile, with varying effects depending on dosage and individual response. The substance is often discussed in the context of its safety and regulatory status, as it has been associated with both therapeutic potential and risks of dependence or adverse effects. As of October 2023, research is ongoing to better understand its mechanisms of action, efficacy, and safety profile, particularly in comparison to conventional opioids. Due to its psychoactive properties, 7-hydroxymitragynine is subject to scrutiny and regulation in various jurisdictions.

Formula: C₂₃H₃₀N₂O₅

InChI: InChI=1S/C23H30N2O5/c1-5-14-12-25-10-9-23(27)20-17(7-6-8-19(20)29-3)24-21(23)18(25)11-15(14)16(13-28-2)22(26)30-4/h6-8,13-15,18,27H,5,9-12H2,1-4H3/b16-13+/t14-,15+,18+,23+/m1/s1

InChI key: InChIKey=RYENLSMHLCNXJT-CYXFISRXSA-N

SMILES: O[C@@]12C=3C(N=C1[C@]4(N(CC2)C[C@@H](CC)[C@@H](\C(\C(OC)=O)=C/OC)C4)[H])=CC=CC3OC

Synonyms:

• Mitragynine hydroxyindolenine
• Corynan-16-carboxylic acid, 1,2,16,17-tetradehydro-2,7-dihydro-7-hydroxy-9,17-dimethoxy-, methyl ester, (7α,16E,20β)-
• 9-Methoxycorynantheidine hydroxyindolenine
• 7α-Hydroxy-7H-mitragynine
• Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethyl-1,2,3,4,6,7,7a,12b-octahydro-7a-hydroxy-8-methoxy-α-(methoxymethylene)-, methyl ester, (αE,2S,3S,7aS,12bS)-

7-Hydroxymitragynine 100 µg/mL in Methanol

Controlled Product

CAS: 174418-82-7

Formula: C₂₃H₃₀N₂O₅

Color and Shape: Single Solution

Molecular weight: 414.49

Ref: 04-A14233650ME-100

7-Hydroxy Mitragynine

CAS: 174418-82-7

Formula: C₂₃H₃₀N₂O₅

Molecular weight: 414.50

Ref: 4Z-M-186002

7-Hydroxy-Mitragynine-13C-d3

CAS: 174418-82-7

Formula: C₂₂₁₃CH₂₇D₃N₂O₅

Molecular weight: 418.51

Ref: 4Z-M-186007

7-Hydroxy mitragynine

Controlled Product

CAS: 174418-82-7

Mitragynine is a monoterpenoid indole alkaloid that is found in the leaves of the plant Mitragyna speciosa. It binds to opioid receptors, which are G-protein coupled receptors located on the cell membrane. Mitragynine has been shown to inhibit mitochondrial membrane potential and receptor activity, which may be due to its ability to inhibit the binding of ATP. This drug also has a pharmacokinetic profile that includes rapid absorption and distribution, with low systemic clearance and a long elimination half-life. Mitragynine has been shown to inhibit recombinant cytochrome P450 enzymes in vitro, as well as rat liver microsomes. Studies have indicated that mitragynine does not produce any physiological effects or symptoms when administered at doses up to 300mg/kg in rats. The drug interactions have not yet been fully investigated, but it is thought that mitragynine may interact with other drugs such as monoamine oxidase inhibitors and clon

Formula: C₂₃H₃₀N₂O₅

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 414.49 g/mol

Ref: 3D-FH74974