CAS 174671-46-6: Tavaborole

Description: Tavaborole is a boron-based antifungal agent primarily used in the treatment of onychomycosis, a fungal infection of the nails. It functions by inhibiting the enzyme leucyl-tRNA synthetase, which is crucial for protein synthesis in fungi, thereby disrupting their growth and reproduction. Tavaborole is characterized by its unique chemical structure, which includes a boron atom that plays a key role in its mechanism of action. The substance is typically administered topically as a solution, allowing for localized treatment with minimal systemic absorption. Its efficacy against various fungal pathogens, including Trichophyton rubrum and Trichophyton mentagrophytes, has been demonstrated in clinical studies. Tavaborole is generally well-tolerated, with a low incidence of side effects, making it a suitable option for patients seeking an effective topical antifungal treatment. Additionally, its formulation allows for easy application and penetration into the nail plate, enhancing its therapeutic potential in treating nail infections.

Formula: C₇H₆BFO₂

InChI: InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2

InChI key: InChIKey=LFQDNHWZDQTITF-UHFFFAOYSA-N

SMILES: FC1=CC=C2B(O)OCC2=C1

Synonyms:

• 2,1-Benzoxaborole, 5-fluoro-1,3-dihydro-1-hydroxy-
• 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
• An 2729
• An-2690
• Kerydin
• Tavaborole
• 5-Fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol

Tavaborole

CAS: 174671-46-6

• Formula: C₇H₆BFO₂
• Purity: >98.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 151.93

2,1-Benzoxaborole, 5-fluoro-1,3-dihydro-1-hydroxy-

CAS: 174671-46-6

• Formula: C₇H₆BFO₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 151.9307

Tavaborole

CAS: 174671-46-6

• Formula: C₇H₆BFO₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 151.93

5-Fluorobenzo[c][1,2]oxaborol-1(3H)-ol

CAS: 174671-46-6

• Purity: 99%
• Molecular weight: 151.93g/mol

Tavaborole

CAS: 174671-46-6

Tavaborole (Kerydin) is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, …

• Formula: C₇H₆BFO₂
• Purity: 98.25% - 99.94%
• Color and Shape: Solid
• Molecular weight: 151.93

Tavaborole

CAS: 174671-46-6

• Formula: C₇H₆BFO₂
• Color and Shape: Neat
• Molecular weight: 151.93

5-Fluorobenzo[c][1,2]oxaborol-1(3H)-ol

CAS: 174671-46-6

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 151.92999267578125

Tavaborole (>90%)

CAS: 174671-46-6

Stability Hygroscopic Applications Tavaborole is a topical treatment of toenail onychomycosis. References Toledo-Bahena, M.E. et. …

• Formula: C₇H₆BFO₂
• Purity: >90%
• Color and Shape: Neat
• Molecular weight: 151.93

1,3-Dihydro-5-fluoro-1-hydroxy-2,1-benzoxaborole

CAS: 174671-46-6

1,3-Dihydro-5-fluoro-1-hydroxy-2,1-benzoxaborole is a chemical compound with antiviral and antifungal properties. It has shown to be …

• Formula: C₇H₆BFO₂
• Purity: Min. 95%
• Molecular weight: 151.93 g/mol