CAS 174671-46-6

Tavaborole

Description:

Tavaborole is a boron-based antifungal agent primarily used in the treatment of onychomycosis, a fungal infection of the nails. It functions by inhibiting the enzyme leucyl-tRNA synthetase, which is crucial for protein synthesis in fungi, thereby disrupting their growth and reproduction. Tavaborole is characterized by its unique chemical structure, which includes a boron atom that plays a key role in its mechanism of action. The substance is typically administered topically as a solution, allowing for localized treatment with minimal systemic absorption. Its efficacy against various fungal pathogens, including Trichophyton rubrum and Trichophyton mentagrophytes, has been demonstrated in clinical studies. Tavaborole is generally well-tolerated, with a low incidence of side effects, making it a suitable option for patients seeking an effective topical antifungal treatment. Additionally, its formulation allows for easy application and penetration into the nail plate, enhancing its therapeutic potential in treating nail infections.

Formula: C₇H₆BFO₂

InChI: InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2

InChI key: InChIKey=LFQDNHWZDQTITF-UHFFFAOYSA-N

SMILES: OB1C=2C(CO1)=CC(F)=CC2

Synonyms:

• 2,1-Benzoxaborole, 5-fluoro-1,3-dihydro-1-hydroxy-
• 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
• An 2729
• An-2690
• Kerydin
• Tavaborole
• 5-Fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol

Tavaborole

CAS: 174671-46-6

Formula: C₇H₆BFO₂

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 151.93

Ref: 3B-T3775

2,1-Benzoxaborole, 5-fluoro-1,3-dihydro-1-hydroxy-

CAS: 174671-46-6

Formula: C₇H₆BFO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 151.9307

Ref: IN-DA001ZVO

Tavaborole

CAS: 174671-46-6

Tavaborole

Purity: ≥98%

Molecular weight: 151.93g/mol

Ref: 54-BUP11206

Tavaborole

CAS: 174671-46-6

Formula: C₇H₆BFO₂

Color and Shape: White To Off-White Solid

Molecular weight: 151.93

Ref: 4Z-T-197001

5-Fluorobenzo[c][1,2]oxaborol-1(3H)-ol

CAS: 174671-46-6

5-Fluorobenzo[c][1,2]oxaborol-1(3H)-ol

Purity: 99%

Molecular weight: 151.93g/mol

Ref: 54-PC908101

Tavaborole

CAS: 174671-46-6

Tavaborole (Kerydin) is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast

Formula: C₇H₆BFO₂

Purity: 99.21% - 99.94%

Color and Shape: Solid

Molecular weight: 151.93

Ref: TM-T3349

Tavaborole

Controlled Product

CAS: 174671-46-6

Formula: C₇H₆BFO₂

Color and Shape: Neat

Molecular weight: 151.93

Ref: TR-T009765

5-Fluorobenzo[c][1,2]oxaborol-1(3H)-ol

CAS: 174671-46-6

Formula: C₇H₆BFO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 151.93

Ref: 10-F425086

Tavaborole (>90%)

Controlled Product

CAS: 174671-46-6

Stability Hygroscopic
Applications Tavaborole is a topical treatment of toenail onychomycosis.
References Toledo-Bahena, M.E. et. al.: J. Drugs Dermatol., 13, 1124 (2014)

Formula: C₇H₆BFO₂

Purity: >90%

Color and Shape: Neat

Molecular weight: 151.93

Ref: TR-T009760

Tavaborole

CAS: 174671-46-6

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₇H₆BFO₂

Molecular weight: 152.04449

Ref: 45-1643373