CAS 174671-46-6
:Tavaborole
Description:
Tavaborole is a boron-based antifungal agent primarily used in the treatment of onychomycosis, a fungal infection of the nails. It functions by inhibiting the enzyme leucyl-tRNA synthetase, which is crucial for protein synthesis in fungi, thereby disrupting their growth and reproduction. Tavaborole is characterized by its unique chemical structure, which includes a boron atom that plays a key role in its mechanism of action. The substance is typically administered topically as a solution, allowing for localized treatment with minimal systemic absorption. Its efficacy against various fungal pathogens, including Trichophyton rubrum and Trichophyton mentagrophytes, has been demonstrated in clinical studies. Tavaborole is generally well-tolerated, with a low incidence of side effects, making it a suitable option for patients seeking an effective topical antifungal treatment. Additionally, its formulation allows for easy application and penetration into the nail plate, enhancing its therapeutic potential in treating nail infections.
Formula:C7H6BFO2
InChI:InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2
InChI key:InChIKey=LFQDNHWZDQTITF-UHFFFAOYSA-N
SMILES:OB1C=2C(CO1)=CC(F)=CC2
Synonyms:- 2,1-Benzoxaborole, 5-fluoro-1,3-dihydro-1-hydroxy-
- 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
- An 2729
- An-2690
- Kerydin
- Tavaborole
- 5-Fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol
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Found 12 products.
Tavaborole
CAS:Formula:C7H6BFO2Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:151.935-Fluorobenzo[c][1,2]oxaborol-1(3H)-ol
CAS:5-Fluorobenzo[c][1,2]oxaborol-1(3H)-olFormula:C7H6BFO2Purity:99%Molecular weight:151.930742,1-Benzoxaborole, 5-fluoro-1,3-dihydro-1-hydroxy-
CAS:Formula:C7H6BFO2Purity:98%Color and Shape:SolidMolecular weight:151.9307Tavaborole
CAS:Tavaborole (Kerydin) is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeastFormula:C7H6BFO2Purity:99.21% - 99.94%Color and Shape:White SolidMolecular weight:151.935-Fluorobenzo[c][1,2]oxaborol-1(3H)-ol
CAS:Formula:C7H6BFO2Purity:98%Color and Shape:SolidMolecular weight:151.93Tavaborole (>90%)
CAS:Controlled ProductStability Hygroscopic
Applications Tavaborole is a topical treatment of toenail onychomycosis.
References Toledo-Bahena, M.E. et. al.: J. Drugs Dermatol., 13, 1124 (2014)Formula:C7H6BFO2Purity:>90%Color and Shape:NeatMolecular weight:151.93Tavaborole
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C7H6BFO2Molecular weight:152.04449
![5-Fluorobenzo[c][1,2]oxaborol-1(3H)-ol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF425086.jpg&w=3840&q=75)
