CAS 1747-60-0

2-Amino-6-methoxybenzothiazole

Description:

2-Amino-6-methoxybenzothiazole is an organic compound characterized by its benzothiazole structure, which consists of a benzene ring fused to a thiazole ring. This compound features an amino group (-NH2) and a methoxy group (-OCH3) at specific positions on the benzothiazole framework, contributing to its chemical reactivity and potential applications. It is typically a solid at room temperature and may exhibit moderate solubility in polar solvents due to the presence of the amino group. The compound is of interest in various fields, including medicinal chemistry, where it may serve as a building block for the synthesis of pharmaceuticals or agrochemicals. Its properties, such as melting point, boiling point, and spectral characteristics, can vary based on purity and environmental conditions. Additionally, 2-amino-6-methoxybenzothiazole may exhibit biological activity, making it a subject of research in drug development and other applications. Safety data should be consulted for handling and usage, as with any chemical substance.

Formula: C₈H₈N₂OS

InChI: InChI=1S/C8H8N2OS/c1-11-5-2-3-6-7(4-5)12-8(9)10-6/h2-4H,1H3,(H2,9,10)

InChI key: InChIKey=KZHGPDSVHSDCMX-UHFFFAOYSA-N

SMILES: NC1=NC=2C(=CC(OC)=CC2)S1

Synonyms:

• (6-Methoxybenzothiazol-2-yl)amine
• 2-Amino-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carbonitrile
• 2-Amino-6-methoxy benzothiazole
• 2-Benzothiazolamine, 6-methoxy-
• 3'-Chlorobiphenyl-4-Carbaldehyde
• 3'-Methoxybiphenyl-4-Carbaldehyde
• 3'-Methylbiphenyl-4-Carbaldehyde
• 3-chloro-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)propanamide
• 6-(Methyloxy)-1,3-benzothiazol-2-amine
• 6-Methoxy-1,3-Benzothiazol-2-Amine
• 6-Methoxy-1,3-Benzothiazol-2-Amine Sulfate (1:1)
• 6-Methoxy-1,3-benzothiazol-2-ylamine
• 6-Methoxy-2-aminobenzothiazole
• 6-Methoxy-2-benzothiazolamine
• 6-Methoxybenzo[D]Thiazol-2-Amine
• 6-Methoxybenzothiazol-2-Ylamine
• Benzothiazole, 2-amino-6-methoxy-
• NSC 27516

2-Amino-6-methoxybenzothiazole

CAS: 1747-60-0

Formula: C₈H₈N₂OS

Purity: >98.0%(T)

Color and Shape: White to Gray to Brown powder to lump

Molecular weight: 180.23

Ref: 3B-A0715

2-Amino-6-methoxybenzothiazole, 98%

CAS: 1747-60-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₈N₂OS

Purity: 98%

Color and Shape: Cream to pale brown, Powder

Molecular weight: 180.23

Ref: 02-B23380

2-Amino-6-methoxy-1,3-benzothiazole

CAS: 1747-60-0

2-Amino-6-methoxy-1,3-benzothiazole

Formula: C₈H₈N₂OS

Purity: tech

Color and Shape: Solid

Molecular weight: 180.22692

Ref: 54-OR18278

2-Amino-6-methoxybenzothiazole

CAS: 1747-60-0

Formula: C₈H₈N₂OS

Molecular weight: 180.23

Ref: 7W-GK3571

6-Methoxybenzo[d]thiazol-2-amine

CAS: 1747-60-0

Formula: C₈H₈N₂OS

Purity: 96%

Color and Shape: Solid

Molecular weight: 180.2269

Ref: IN-DA001ZWE

2-Amino-6-methoxybenzothiazole

CAS: 1747-60-0

2-Amino-6-methoxybenzothiazole

Formula: C₈H₈N₂OS

Purity: 97%

Molecular weight: 180.23

Ref: IN-DG6366

2-Amino-6-methoxybenzothiazole

CAS: 1747-60-0

2-Amino-6-methoxybenzothiazole is a drug that is used to treat cervical cancer. It has inhibitory properties against the growth of human tumor cells in vitro. The inhibition of cell proliferation was shown to be mediated by the hydroxyl group, which interacts with the methyl ketones, leading to a decrease in the Langmuir adsorption isotherm. 2-Amino-6-methoxybenzothiazole also inhibits sodium carbonate and hydrochloric acid, which are important for transcription and translation of DNA. This drug has been shown to have no effect on proton NMR spectra or amines, but does react with coumarin derivatives. The reaction mechanism may involve an inorganic acid such as nitric acid or phosphoric acid.

Formula: C₈H₈N₂OS

Purity: Min. 95%

Molecular weight: 180.23 g/mol

Ref: 3D-FA35370

2-Amino-6-methoxybenzothiazole

CAS: 1747-60-0

Formula: C₈H₈N₂OS

Purity: 96%

Color and Shape: Solid

Molecular weight: 180.23

Ref: 10-F048096

2-Amino-6-methoxybenzothiazole

Controlled Product

CAS: 1747-60-0

Applications 2-Amino-6-methoxybenzothiazole is an intermediate used to prepare novel series of Schiff bases and 4-thiazolidinones. It is also used in the synthesis of 2-cyano-6-methoxybenzothiazole.
References Patel, N., et al.: Saudi Pharma. J., 18, 129 (2010); Toya, Y., et al.: Bull. Chem. Soc. Jpn., 65, 392 (1992)

Formula: C₈H₈N₂OS

Color and Shape: Neat

Molecular weight: 180.23

Ref: TR-A611445