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CAS 174794-02-6

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OLANZAPINE N-OXIDE

Description:
Olanzapine N-oxide is a chemical compound derived from olanzapine, an atypical antipsychotic medication primarily used to treat schizophrenia and bipolar disorder. The N-oxide form is characterized by the presence of an oxidized nitrogen atom, which alters its pharmacological properties compared to the parent compound. This modification can influence its solubility, stability, and interaction with biological targets. Olanzapine N-oxide is typically a white to off-white solid, and it is soluble in organic solvents. Its molecular structure includes a thienobenzodiazepine core, which is essential for its activity. The compound is of interest in pharmacological research, particularly in understanding the mechanisms of action of antipsychotic drugs and their metabolites. Additionally, the N-oxide form may exhibit different affinities for neurotransmitter receptors, potentially leading to variations in therapeutic effects and side effects. As with many pharmaceutical compounds, safety and efficacy profiles are critical, and ongoing studies may further elucidate its role in clinical settings.
Formula:C17H20N4OS
InChI:InChI=1/C17H20N4OS/c1-12-11-13-16(20-7-9-21(2,22)10-8-20)18-14-5-3-4-6-15(14)19-17(13)23-12/h3-6,11,19H,7-10H2,1-2H3
SMILES:Cc1cc2C(=Nc3ccccc3Nc2s1)N1CCN(=O)(C)CC1
Synonyms:
  • Ly 170238
  • 2-Methyl-4-(4-methyl-4-oxido-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
  • 2-methyl-4-(4-methyl-4-oxidopiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
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