CAS 17515-77-4

2-(bromomethyl)-5-(trifluoromethyl)furan

Description:

2-(Bromomethyl)-5-(trifluoromethyl)furan is a chemical compound characterized by its furan ring, which is a five-membered aromatic heterocycle containing one oxygen atom. The presence of a bromomethyl group at the 2-position and a trifluoromethyl group at the 5-position significantly influences its chemical reactivity and physical properties. This compound is typically a colorless to pale yellow liquid or solid, depending on its purity and specific conditions. It exhibits notable polar characteristics due to the electronegative trifluoromethyl group, which can enhance its reactivity in nucleophilic substitution reactions. The bromomethyl group serves as a versatile functional handle for further chemical modifications. Additionally, the compound may exhibit biological activity, making it of interest in medicinal chemistry and material science. Its CAS number, 17515-77-4, allows for easy identification in chemical databases. Safety precautions should be taken when handling this compound, as it may pose health risks due to the presence of bromine and fluorine atoms.

Formula: C₆H₄BrF₃O

InChI: InChI=1/C14H15F6NO4S2/c1-25-12(22)11(3-4-26-2)21-27(23,24)10-6-8(13(15,16)17)5-9(7-10)14(18,19)20/h5-7,11,21H,3-4H2,1-2H3

SMILES: COC(=O)C(CCSC)NS(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

Synonyms:

• methyl N-{[3,5-bis(trifluoromethyl)phenyl]sulfonyl}methioninate
• 2-Bromomethyl-5-Trifluoromethylfurane
• 2-(Bromomethyl)-5-(trifluoromethyl)furan97%
• 2-(BROMOMETHYL)-5-(TRIFLUOROMETHYL)FURAN
• Furan,2-(broMoMethyl)-5-(trifluoroMethyl)-
• 2-(Bromomethyl)-5-(trifluoromethyl)furane
• 2-(Bromomethyl)-5-(trifluoromethyl)furan 97%

2-(Bromomethyl)-5-(trifluoromethyl)furan

CAS: 17515-77-4

Formula: C₆H₄BrF₃O

Purity: >97.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 229.00

Ref: 3B-B5800

Furan, 2-(bromomethyl)-5-(trifluoromethyl)-

CAS: 17515-77-4

Formula: C₆H₄BrF₃O

Purity: 98%

Color and Shape: Liquid

Molecular weight: 228.9946

Ref: IN-DA0020D9

2-(Bromomethyl)-5-(trifluoromethyl)furan

CAS: 17515-77-4

2-(Bromomethyl)-5-(trifluoromethyl)furan

Formula: C₆H₄BrF₃O

Purity: 95%

Color and Shape: colourless liquid

Molecular weight: 228.99g/mol

Ref: 54-PC2459

2-(Bromomethyl)-5-(trifluoromethyl)furan

CAS: 17515-77-4

Formula: C₆H₄BrF₃O

Purity: 98%

Color and Shape: Liquid, No data available.

Molecular weight: 228.996

Ref: 10-F067833

2-(Bromomethyl)-5-(trifluoromethyl)furan

Controlled Product

CAS: 17515-77-4

Applications 2-(Bromomethyl)-5-(trifluoromethyl)furan is an intermediate used to prepare tertiary sulfonamides as liver X receptor antagonists. It is also used to synthesize hydantoin based inhibitors of MMP13 with potential use in osteoarthritis.
References Zuercher, W., et al.: J. Med. Chem., 53, 3412 (2010); De Savi, C., et al.: Bioorg. Med. Chem. Lett., 23, 4705 (2013)

Formula: C₆H₄BrF₃O

Color and Shape: Neat

Molecular weight: 228.99

Ref: TR-B687925