CAS 176161-24-3

Maribavir

Description:

Maribavir is an antiviral compound primarily investigated for its efficacy against cytomegalovirus (CMV) infections, particularly in immunocompromised patients, such as those undergoing organ transplantation or with HIV/AIDS. It belongs to the class of compounds known as benzimidazoles and functions by inhibiting the viral replication process. Maribavir exhibits a unique mechanism of action by targeting the viral UL97 kinase, which is crucial for CMV replication and maturation. The substance is characterized by its moderate solubility in water and stability under various pH conditions, making it suitable for oral administration. In clinical studies, Maribavir has shown a favorable safety profile, with common side effects being generally mild. Its development represents a significant advancement in antiviral therapy, particularly for patients who are resistant to other treatments. As research continues, Maribavir's potential applications may expand, contributing to the broader field of antiviral drug development.

Formula: C₁₅H₁₉Cl₂N₃O₄

InChI: InChI=1S/C15H19Cl2N3O4/c1-6(2)18-15-19-9-3-7(16)8(17)4-10(9)20(15)14-13(23)12(22)11(5-21)24-14/h3-4,6,11-14,21-23H,5H2,1-2H3,(H,18,19)/t11-,12-,13-,14-/m0/s1

InChI key: InChIKey=KJFBVJALEQWJBS-XUXIUFHCSA-N

SMILES: N(C(C)C)C=1N(C=2C(N1)=CC(Cl)=C(Cl)C2)[C@H]3O[C@@H](CO)[C@H](O)[C@@H]3O

Synonyms:

• 1263W94
• 1H-Benzimidazol-2-amine, 5,6-dichloro-N-(1-methylethyl)-1-β-<span class="text-smallcaps">L</span>-ribofuranosyl-
• 5,6-Dichloro-2-(Isopropylamino)-1-(Beta-L-Ribofuranosyl)-1H-Benzimidazole
• 5,6-Dichloro-2-Isopropylamino-1-(-L-Ribofuranosyl)-Lh-Benzimidazole
• 5,6-Dichloro-N-(1-methylethyl)-1-β-<span class="text-smallcaps">L</span>-ribofuranosyl-1H-benzimidazol-2-amine
• 5,6-dichloro-1-[(1S)-pentofuranosyl]-N-(propan-2-yl)-1H-benzimidazol-2-amine
• 5,6-dichloro-N-(1-methylethyl)-1-beta-L-ribofuranosyl-1H-benzimidazol-2-amine
• BENZIMIDAVIR, 5,6-DICHLORO-2-(ISOPROPYLAMINO)-1-(β-L-RIBOFURANOSYL)-LH-BENZIMIDAZOLE
• Benzimidavir: 5,6-Dichloro-2-(Isopropylamino)-1-(Ss-L-Ribofuranosyl)-Lh-Benzimidazole
• Bw 1263W94
• Gw 257406X
• Maribavir
• 1H-Benzimidazol-2-amine, 5,6-dichloro-N-(1-methylethyl)-1-β-L-ribofuranosyl-

Maribavir

CAS: 176161-24-3

(2S,3S,4R,5S)-2-(5,6-Dichloro-2-(isopropylamino)-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Formula: C₁₅H₁₉Cl₂N₃O₄

Purity: 98%

Molecular weight: 376.24

Ref: IN-DG115638

BENZIMIDAVIR

CAS: 176161-24-3

Formula: C₁₅H₁₉Cl₂N₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 376.2351

Ref: IN-DA00AQ58

Maribavir

CAS: 176161-24-3

Maribavir

Formula: C₁₅H₁₉Cl₂N₃O₄

Purity: ≥98%

Molecular weight: 376.24

Ref: 54-BUP07244

Maribavir-d7

CAS: 176161-24-3

Formula: C₁₅H₁₂D₇Cl₂N₃O₄

Molecular weight: 383.28

Ref: 4Z-M-304002

Maribavir

CAS: 176161-24-3

Formula: C₁₅H₁₉Cl₂N₃O₄

Molecular weight: 376.23

Ref: 4Z-M-304001

Maribavir

CAS: 176161-24-3

Maribavir (GW257406X), an oral anti-CMV benzimidazole riboside, targets UL97 kinase, effective on resistant strains.

Formula: C₁₅H₁₉Cl₂N₃O₄

Purity: 99.99% - >99.99%

Color and Shape: White Solid

Molecular weight: 376.24

Ref: TM-T2162

Maribavir

CAS: 176161-24-3

Formula: C₁₅H₁₉Cl₂N₃O₄

Molecular weight: 376.23

Ref: ST-EA-CP-M75000

Maribavir

CAS: 176161-24-3

Potent antiviral against HCMV and Epstein-Barr virus (EBV)

Formula: C₁₅H₁₉Cl₂N₃O₄

Purity: Min. 95%

Molecular weight: 376.24 g/mol

Ref: 3D-AM178224