CAS 17630-75-0

5-Chlorooxindole

Description:

5-Chlorooxindole is a chemical compound characterized by its oxindole structure, which consists of a bicyclic framework containing an indole moiety fused to a carbonyl group. The presence of a chlorine atom at the 5-position of the oxindole ring significantly influences its chemical properties and reactivity. This compound is typically a white to off-white solid and is known for its role in various chemical reactions, including those in medicinal chemistry and organic synthesis. 5-Chlorooxindole can participate in nucleophilic substitution reactions due to the electrophilic nature of the carbon adjacent to the chlorine atom. It has been studied for its potential biological activities, including anti-inflammatory and anticancer properties. Additionally, its derivatives may exhibit varied pharmacological effects, making it a subject of interest in drug development. As with many chemical substances, handling 5-chlorooxindole requires appropriate safety precautions due to its potential toxicity and reactivity.

Formula: C₈H₆ClNO

InChI: InChI=1/C8H4ClNO/c9-6-1-2-7-5(3-6)4-8(11)10-7/h1-4H

InChI key: InChIKey=WWJLCYHYLZZXBE-UHFFFAOYSA-N

SMILES: O=C1NC=2C(C1)=CC(Cl)=CC2

Synonyms:

• 2-Indolinone, 5-chloro-
• 2H-Indol-2-one, 5-chloro-1,3-dihydro-
• 5-Chloro-1,3-dihydroindol-2-one
• 5-Chloro-1,3-dihydroindole-2-one
• 5-Chloro-2-oxindole
• 5-Chloro-2-oxoindoline
• 5-Chloroindol-2-one
• 5-Chloroindolin-2-one
• 5-Chloroxindole
• 5-chloro-1,3-dihydro-2H-indol-2-one
• 5-chloro-2-Indolinone
• 5-chloro-2H-indol-2-one
• Akos 205-23
• Akos Bbs-00006437
• Oxindole, 5-chloro-
• 5-Chlorooxindole
• 5-CHLORO-1,3-DIHYDRO-INDOL-2-ONE
• 5-CHLOROINDOLIN-2-ONE 5-CHLOROOXINDOLE 5-CHLORO-1,3-DIHYDROINDOLE-2-ONE
• 5-Chlorooxindole ,99%
• TIMTEC-BB SBB003879
• 5-Chloro-1H-indol-2(3H)-one
• 5-CHLOROINDOLINE-2-ONE
• 4-chloroindole-2(3h)-one
• 5-CHLOROOXINDOLE, 97+%
• 3-dihydroindole-2-one
• 5-CHLOROINDOLE-2-ONE

5-Chlorooxindole

CAS: 17630-75-0

Formula: C₈H₆ClNO

Purity: >97.0%(GC)(N)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 167.59

Ref: 3B-C1509

5-Chlorooxindole, 98%

CAS: 17630-75-0

5-Chloro-2-oxindole was used for the quantitation of 5-chloro-2-oxindole, concomitantly with all of its potential positional isomers using a single, highly specific, normal-phase chromatographic system. 5-Chloro-2-oxindole (5-Chlorooxindole) is a starting material for tenidap sodium, a pharmaceutica

Formula: C₈H₆ClNO

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, White to cream to pink to pale brown

Molecular weight: 167.6

Ref: 02-A19210

5-Chloro-2-oxindole

CAS: 17630-75-0

5-Chloro-2-oxindole

Formula: C₈H₆ClNO

Purity: 95%

Color and Shape: Off-white Solid

Molecular weight: 167.59234

Ref: 54-OR51359

5-Chloro-2-oxindole

CAS: 17630-75-0

5-Chloro-2-oxindole

Formula: C₈H₆ClNO

Purity: 97%

Color and Shape: Solid

Molecular weight: 167.59234

Ref: 54-OR10940

5-Chlorooxindole

CAS: 17630-75-0

Formula: C₈H₆ClNO

Molecular weight: 167.60

Ref: 7W-GK3218

5-Chloro-1,3-dihydro-2H-indol-2-one

CAS: 17630-75-0

Formula: C₈H₆ClNO

Purity: 97%

Color and Shape: Solid

Molecular weight: 167.5923

Ref: IN-DA0024K1

5-Chlorooxindole

CAS: 17630-75-0

5-Chlorooxindole is a synthetic, chemotherapeutic drug that has been shown to have anti-tumor activity in animal models. It is an oxindole derivative with the chemical formula CHNClO. The compound is synthesized by the reaction of 3,5-dichloroaniline and indole in chloroform and purified by column chromatography. 5-Chlorooxindole has shown potential as an antitumor agent because it inhibits cancer cell growth through mechanisms such as induction of apoptosis and suppression of tumor angiogenesis.

Formula: C₈H₆ClNO

Purity: Min. 95%

Molecular weight: 167.59 g/mol

Ref: 3D-FC03026

5-Chlorooxindole

CAS: 17630-75-0

Formula: C₈H₆ClNO

Purity: 95%

Color and Shape: Solid

Molecular weight: 167.59

Ref: 10-F024250

5-Chloro-2-oxindole

CAS: 17630-75-0

5-Chloro-2-oxindole

Formula: C₈H₆ClNO

Purity: 97%

Molecular weight: 167.59

Ref: IN-DG8395

5-Chloro-2-oxindole

Controlled Product

CAS: 17630-75-0

Applications 5-Chloro-2-oxindole is used in the preparation of novel GSK-3β inhibitors as anticancer agents.
References Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);

Formula: C₈H₆ClNO

Color and Shape: Neat

Molecular weight: 167.592

Ref: TR-C375030