CAS 17692-51-2
:metergoline
Description:
Metergoline is a chemical compound classified as a serotonin receptor antagonist, primarily targeting the 5-HT2 receptor subtype. It is known for its potential applications in the field of neuroscience and psychopharmacology, particularly in the study of mood disorders and psychotic conditions. Metergoline exhibits a complex structure that includes an indole moiety, which is characteristic of many serotonin-related compounds. The substance is typically administered in research settings, and its pharmacological profile suggests that it may influence various neurotransmitter systems, potentially affecting mood and perception. Metergoline has been investigated for its effects on both central and peripheral serotonin pathways, contributing to its interest in therapeutic contexts. However, like many compounds in this category, it may also present side effects and requires careful consideration in terms of dosage and administration. As with any pharmacological agent, ongoing research is essential to fully understand its mechanisms of action and potential therapeutic benefits.
Formula:C25H29N3O2
InChI:InChI=1/C25H29N3O2/c1-27-14-18(13-26-25(29)30-16-17-7-4-3-5-8-17)11-21-20-9-6-10-22-24(20)19(12-23(21)27)15-28(22)2/h3-10,15,18,21,23H,11-14,16H2,1-2H3,(H,26,29)/p+1/t18-,21+,23+/m0/s1
InChI key:InChIKey=WZHJKEUHNJHDLS-QTGUNEKASA-N
SMILES:CN1C2=C3C([C@@]4([C@@](CC3=C1)(N(C)C[C@H](CNC(OCC5=CC=CC=C5)=O)C4)[H])[H])=CC=C2
Synonyms:- (((8-beta)-1,6-Dimethylergolin-8-yl)methyl)carbamic acid phenylmethyl ester
- (+)-N-(Carboxy)-1-methyl-9,10-dihydrolysergamine benzyl ester
- (+)-N-Carboxy-1-methyl-9,10-dihydrolysergamide benzyl ester
- 1,6-Dimethyl-8-beta-carbobenzyloxaminomethyl-10-alpha-ergoline
- 1-Methyl-8-beta-carbobenzyloxyaminomethyl-10-alpha-ergoline
- 1-Methyl-N-carbobenzyloxydihydro-D-lysergamin
- 8β-Carbobenzyloxyaminomethyl-1,6-dimethyl-10α-ergoline
- <span class="text-smallcaps">D</span>-8β-[(Carbobenzoxyamino)methyl]-1,6-dimethyl-10α-ergoline
- <span class="text-smallcaps">D</span>-8β-[(Carboxyamino)methyl]-1,6-dimethylergoline I benzyl ester
- <span class="text-smallcaps">D</span>-N-Carbobenzoxydihydro-1-methyllysergamine I
- <span class="text-smallcaps">D</span>-N-Carboxydihydro-1-methyllysergamine I benzyl ester
- <span class="text-smallcaps">D</span>-[(4,6,6a,7,8,9,10,10a-Octahydro-4,7-dimethyl-10aα-indolo[4,3-fg]quinolin-9β-yl)methyl]carbamic acid benzyl ester
- Ahr 3009
- Benzyl 1,6-dimethylergolin-8beta-ylmethylcarbamat
- Benzyl {[(5Xi,10Beta)-1,6-Dimethylergolin-8-Yl]Methyl}Carbamate
- Benzyl {[(8Beta)-1,6-Dimethylergolin-6-Ium-8-Yl]Methyl}Carbamate
- Benzyl {[(8Beta)-1,6-Dimethylergolin-8-Yl]Methyl}Carbamate
- Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, benzyl ester
- Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, phenylmethyl ester (9CI)
- Carbamic acid, (((8beta)-1,6-dimethylergolin-8-yl)methyl)-, phenylmethyl ester
- Carbamic acid, ((1,6-dimethylergolin-8-beta-yl)methyl)-, benzyl ester
- Carbamic acid, N-[[(8β)-1,6-dimethylergolin-8-yl]methyl]-, phenylmethyl ester
- Carbamic acid, [(1,6-dimethylergolin-8β-yl)methyl]-, benzyl ester
- Carbamic acid, [[(8β)-1,6-dimethylergolin-8-yl]methyl]-, phenylmethyl ester
- Contralac
- D-8-beta-((Carbobenzoxyamino)methyl)-1,6-dimethyl-10-alpha-ergoline
- D-8-beta-((Carboxyamino)methyl)-1,6-dimethylergoline I benzyl ester
- D-N-Carbobenzoxydihydro-1-methyllysergamine I
- D-N-Carboxydihydro-1-methyllysergamine I benzyl ester
- Ergoline, carbamic acid deriv.
- Fi 6337
- Indolo[4,3-fg]quinoline, carbamic acid deriv.
- Liserdol
- Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester
- Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester (7CI)
- MCE
- Metergolin
- Metergolina
- Metergolina [DCIT]
- Metergolina [Spanish]
- Metergoline [INN:BAN]
- Metergolinum
- Metergolinum [INN-Latin]
- Metergolinum [Latin]
- Methergoline
- Substance 355/255
- Unii-1501393Ly5
- Metergoline
- [((8BETA)-1,6-DIMETHYLERGOLIN-8-YL)METHYL]CARBAMIC ACID PHENYLMETHYL ESTER
- (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-carbamicaciphenylmethylest
- d-n-carbobenzoxydihydro-1-methyllysergaminei
- ((1,6-dimethylergolin-8-beta-yl)methyl)-carbamicacibenzylester
- d-n-carboxydihydro-1-methyllysergamineibenzylester
- ahr3009
- N-CBZ-[(8BETA)-1,6-DIMETHYLERGOLIN-8-YL]METHYLAMINE
- (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-carbamicacibenzylester
- METERGOLINE PHENYLMETHYL ESTER
- See more synonyms
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Metergoline
CAS:Applications Metergoline is an antagonist at 5-HT1, 5-HT2, and 5-HT7 serotonin receptors. Metergoline is an analgesic; antipyretic.
References Aulakh, et al.: J. Pharmacol. Exp. Ther., 263, 588 (1992), Miller, et al.: Eur. J. Pharmacol., 227, 99 (1992),Formula:C25H29N3O2Color and Shape:NeatMolecular weight:403.5167Metergoline
CAS:Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist.Formula:C25H29N3O2Purity:99.83% - 99.97%Color and Shape:SolidMolecular weight:403.5167[(8b)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester
CAS:Ergolines are a class of drugs that bind to serotonin receptors. The ergoline derivative [(8b)-1,6-dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester (DMPE) is a potent and selective 5-hydroxytryptamine (5-HT) receptor antagonist. DMPE has been shown to have the ability to increase serum prolactin levels in rats and antagonize the effects of metergoline in monkeys. It also reduces blood pressure in animals by blocking the vasoconstrictor effect of 5-HT on vascular smooth muscle cells.Formula:C25H29N3O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:403.52 g/mol
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