CAS 1781834-99-8

Formula: C22H23F5N4O4S

InChI: InChI=1S/C20H22F2N4O2S.C2HF3O2/c1-25(28-2)19(27)26-20(11-6-12-23,14-7-4-3-5-8-14)29-18(24-26)16-13-15(21)9-10-17(16)22;3-2(4,5)1(6)7/h3-5,7-10,13H,6,11-12,23H2,1-2H3;(H,6,7)/t20-;/m0./s1

InChI key: CIJUJPVFECBUKG-BDQAORGHSA-N

SMILES: CN(C(=O)N1[C@](SC(=N1)C2=C(C=CC(=C2)F)F)(CCCN)C3=CC=CC=C3)OC.C(=O)(C(F)(F)F)O

Filanesib TFA

CAS: 1781834-99-8

Filanesib (ARRY-520) inhibits KSP, triggering mitotic arrest and cell death in dividing tumor cells.

Formula: C₂₂H₂₃F₅N₄O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 534.5

Ref: TM-T25418

Filanesib TFA

CAS: 1781834-99-8

Filanesib is a small molecule that binds to ion channels and modifies the function of these channels. It is used as a research tool in cell biology and pharmacology. Filanesib binds to the extracellular domain of GABA A receptor and blocks the channel, leading to an increase in neuronal activity. This compound also has been shown to be a potent inhibitor of G protein-coupled receptors (GPCRs).

Formula: C₂₂H₂₃F₅N₄O₄S

Purity: Min. 95%

Molecular weight: 534.5 g/mol

Ref: 3D-GWC83499