CAS 17902-23-7: Tegafur

Description: Tegafur, with the CAS number 17902-23-7, is an antineoplastic agent primarily used in cancer therapy, particularly for gastrointestinal cancers. It is a prodrug of 5-fluorouracil (5-FU), meaning that it is metabolized in the body to produce the active chemotherapeutic agent. Tegafur is typically administered in combination with other agents, such as uracil, to enhance its efficacy and reduce toxicity. The compound is characterized by its ability to inhibit DNA synthesis, thereby impeding the proliferation of cancer cells. It is usually presented in oral dosage forms and is known for its relatively favorable pharmacokinetic profile, allowing for sustained drug levels in the body. Common side effects may include gastrointestinal disturbances, myelosuppression, and fatigue, reflecting its impact on rapidly dividing cells. As with any chemotherapeutic agent, careful monitoring and dosage adjustments are essential to optimize therapeutic outcomes while minimizing adverse effects.

Formula: C₈H₉FN₂O₃

InChI: InChI=1S/C8H9FN2O3/c9-5-4-11(6-2-1-3-14-6)8(13)10-7(5)12/h4,6H,1-3H2,(H,10,12,13)

InChI key: InChIKey=WFWLQNSHRPWKFK-UHFFFAOYSA-N

SMILES: O=C1NC(=O)N(C=C1F)C2OCCC2

Synonyms:

• 1-(2'-Tetrahydrofuryl)-5-fluorouracil
• 1-(Tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione
• 1-(Tetrahydro-2-furanyl)-5-fluorouracil
• 1-Naphthol-3,8-Disulfonic Acid
• 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-
• 5-Fluor-1-(tetrahydro-2-furyl)uracil
• 5-Fluoro-1-(2-tetrahydrofuranyl)uracil
• 5-Fluoro-1-(Tetrahidro-2-Furil)Uracilo
• 5-Fluoro-1-(Tetrahydrofuran-2-Yl)Uracil
• 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione
• 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione
• 5-Fluoro-1-(tetrahydro-2-furfuryl)uracil
• 5-Fluoro-1-(tetrahydro-2-furyl)uracil
• 5-Fluoro-1-(tetrahydro-2-furyl)uracile
• 5-Fluoro-1-Oxolan-2-Yl-Pyrimidine-2,4-Dione
• 5-fluoro-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
• 5-fluoro-1-[(2R)-tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione
• Citofur
• Coparogin
• Epsilone Acid
• Exonal
• Fental
• Fluaid
• Fluorafur
• Fluorofur
• Franrose
• Ft 207
• Fulaid
• Fulfeel
• Furafluor
• Furofutran
• Futraful
• Lamar
• Lifril
• Mjf 12264
• N1-(2'-Tetrahydrofuryl)-5-fluorouracil
• N1-(2-Tetrahydrofuranyl)-5-fluorouracil
• N¹-(2-Tetrahydrofuranyl)-5-fluorouracil
• N¹-(2-Tetrahydrofuryl)-5-fluorouracil
• Neberk
• Nitobanil
• Nsc 148-958
• Nsc 148958
• Racemic Ftorafur
• Riol
• Sinoflurol
• Sunfural
• Tefsiel C
• Tegafur
• Ts 1
• Uracil, 5-fluoro-1-(tetrahydro-2-furyl)-
• Utefos

Tegafur

CAS: 17902-23-7

Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity.

• Formula: C₈H₉FN₂O₃
• Purity: 99.16% - 99.89%
• Color and Shape: White Crystalline Powder
• Molecular weight: 200.17

Tegafur

CAS: 17902-23-7

• Formula: C₈H₉FN₂O₃
• Purity: %
• Color and Shape: Solid
• Molecular weight: 200.1671

Tegafur

CAS: 17902-23-7

• Purity: 99.16%
• Molecular weight: 200.17g/mol

Tegafur

CAS: 17902-23-7

• Formula: C₈H₉FN₂O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 200.17

Tegafur

CAS: 17902-23-7

• Formula: C₈H₉FN₂O₃
• Molecular weight: 200.17

5-Fluoro-1-(tetrahydro-2-furyl)uracil

CAS: 17902-23-7

• Purity: 98+%
• Molecular weight: 200.17g/mol

5-Fluoro-1-(tetrahydro-2-furfuryl)uracil

CAS: 17902-23-7

• Formula: C₈H₉FN₂O₃
• Purity: >98.0%(HPLC)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 200.17

Tegafur-d7

CAS: 17902-23-7

• Formula: C₈H₂D₇FN₂O₃
• Molecular weight: 207.21

Tegafur

CAS: 17902-23-7

• Formula: C₈H₉FN₂O₃
• Color and Shape: White
• Molecular weight: 200.17

5-Fluoro-1-(tetrahydro-2-furyl)uracil

CAS: 17902-23-7

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• Formula: C₈H₉FN₂O₃
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 200.17 g/mol