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CAS 17902-23-7

:

Tegafur

Description:
Tegafur, with the CAS number 17902-23-7, is an antineoplastic agent primarily used in cancer therapy, particularly for gastrointestinal cancers. It is a prodrug of 5-fluorouracil (5-FU), meaning that it is metabolized in the body to produce the active chemotherapeutic agent. Tegafur is typically administered in combination with other agents, such as uracil, to enhance its efficacy and reduce toxicity. The compound is characterized by its ability to inhibit DNA synthesis, thereby impeding the proliferation of cancer cells. It is usually presented in oral dosage forms and is known for its relatively favorable pharmacokinetic profile, allowing for sustained drug levels in the body. Common side effects may include gastrointestinal disturbances, myelosuppression, and fatigue, reflecting its impact on rapidly dividing cells. As with any chemotherapeutic agent, careful monitoring and dosage adjustments are essential to optimize therapeutic outcomes while minimizing adverse effects.
Formula:C8H9FN2O3
InChI:InChI=1S/C8H9FN2O3/c9-5-4-11(6-2-1-3-14-6)8(13)10-7(5)12/h4,6H,1-3H2,(H,10,12,13)
InChI key:InChIKey=WFWLQNSHRPWKFK-UHFFFAOYSA-N
SMILES:O=C1N(C=C(F)C(=O)N1)C2CCCO2
Synonyms:
  • 1-(2'-Tetrahydrofuryl)-5-fluorouracil
  • 1-(Tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione
  • 1-(Tetrahydro-2-furanyl)-5-fluorouracil
  • 1-Naphthol-3,8-Disulfonic Acid
  • 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-
  • 5-Fluor-1-(tetrahydro-2-furyl)uracil
  • 5-Fluoro-1-(2-tetrahydrofuranyl)uracil
  • 5-Fluoro-1-(Tetrahidro-2-Furil)Uracilo
  • 5-Fluoro-1-(Tetrahydrofuran-2-Yl)Uracil
  • 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione
  • See more synonyms
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Found 11 products.
  • Tegafur

    CAS:
    <p>Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity.</p>
    Formula:C8H9FN2O3
    Purity:99.16% - 99.89%
    Color and Shape:White Crystalline Powder
    Molecular weight:200.17
  • Tegafur

    CAS:
    Formula:C8H9FN2O3
    Purity:%
    Color and Shape:Solid
    Molecular weight:200.1671

    Ref: IN-DA003UHZ

    5g
    31.00€
    10g
    46.00€
    25g
    57.00€
    100g
    120.00€
    500g
    304.00€
  • Tegafur

    CAS:
    <p>Tegafur</p>
    Purity:≥98%
    Molecular weight:200.17g/mol

    Ref: 54-BUP14723

    1g
    193.00€
    25mg
    51.00€
    50mg
    59.00€
    100mg
    85.00€
    500mg
    147.00€
  • Tegafur

    CAS:
    Formula:C8H9FN2O3
    Color and Shape:White To Off-White Solid
    Molecular weight:200.17

    Ref: 4Z-T-239001

    5mg
    To inquire
    10mg
    444.00€
    25mg
    635.00€
    50mg
    825.00€
    100mg
    To inquire
  • Tegafur

    CAS:
    Formula:C8H9FN2O3
    Molecular weight:200.17

    Ref: 7W-GP7239

    ne
    To inquire
  • 5-Fluoro-1-(tetrahydro-2-furyl)uracil

    CAS:
    <p>5-Fluoro-1-(tetrahydro-2-furyl)uracil</p>
    Purity:98%
    Molecular weight:200.17g/mol

    Ref: 54-PC450272

    5g
    32.00€
    25g
    51.00€
    100g
    136.00€
    500g
    406.00€
    2.5kg
    1,680.00€
  • 5-Fluoro-1-(tetrahydro-2-furfuryl)uracil

    CAS:
    Formula:C8H9FN2O3
    Purity:>98.0%(HPLC)(N)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:200.17

    Ref: 3B-F0635

    5g
    43.00€
    25g
    101.00€
  • Tegafur-d7

    CAS:
    Formula:C8H2D7FN2O3
    Molecular weight:207.21

    Ref: 4Z-T-239002

    5mg
    To inquire
    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Tegafur

    Controlled Product
    CAS:
    Formula:C8H9FN2O3
    Color and Shape:White
    Molecular weight:200.17

    Ref: TR-T013900

    1g
    219.00€
    5mg
    105.00€
    50mg
    191.00€
  • 5-Fluoro-1-(tetrahydro-2-furyl)uracil

    CAS:
    <p>5-Fluoro-1-(tetrahydro-2-furyl)uracil is a chemotherapeutic agent, which is a synthetic derivative of uracil. This compound is developed from modified nucleosides with the aim of enhancing antitumor efficacy. Its mechanism of action involves the inhibition of thymidylate synthase, leading to a disruption in DNA synthesis. By integrating into RNA and DNA, it ultimately impedes tumor cell proliferation due to RNA processing interference and DNA damage.</p>
    Formula:C8H9FN2O3
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:200.17 g/mol

    Ref: 3D-FF08013

    10g
    135.00€
    25g
    166.00€
    50g
    280.00€
  • Ref: 10-F815549

    5g
    23.00€
    10g
    36.00€
    25g
    50.00€
    100g
    147.00€
    500g
    455.00€