CAS 179386-44-8

5(R)-(Methylamino)-2,4,5,6-tetrahydro-1H-imidazo[4,5,1-ij]quinolin-2-one maleate

Description:

5(R)-(Methylamino)-2,4,5,6-tetrahydro-1H-imidazo[4,5,1-ij]quinolin-2-one maleate, with CAS number 179386-44-8, is a chemical compound characterized by its complex bicyclic structure, which includes an imidazoquinoline core. This compound typically exhibits properties associated with its functional groups, such as basicity due to the presence of the methylamino group. It is often studied for its potential pharmacological applications, particularly in the field of medicinal chemistry, where it may exhibit biological activity against various targets. The maleate salt form indicates that it is combined with maleic acid, which can enhance its solubility and stability. The compound's stereochemistry, denoted by the (R) configuration, suggests specific spatial arrangements that can influence its biological interactions. Overall, this substance is of interest for its potential therapeutic uses, and its characteristics are defined by its molecular structure, solubility, and biological activity.

Formula: C₁₅H₁₇N₃O₅

Synonyms:

• Sumanirole maleate
• U-95666(free base)
• U-95666E
• Pnu-95666E
• Pnu-95666A
• U-95666A

Sumanirole (maleate)

CAS: 179386-44-8

Formula: C₁₅H₁₇N₃O₅

Purity: 99.0%

Color and Shape: Solid

Molecular weight: 319.3126

Ref: IN-DA00ABYY

Sumanirole maleate

CAS: 179386-44-8

Sumanirole maleate

Purity: ≥95%

Molecular weight: 319.31g/mol

Ref: 54-BUP21743

Sumanirole maleate

CAS: 179386-44-8

Formula: C₁₅H₁₇N₃O₅

Purity: ≥ 98.0%

Color and Shape: White to beige powder

Molecular weight: 319.31

Ref: 7W-GP9600

Sumanirole maleate

CAS: 179386-44-8

Sumanirole maleate (PNU-95666E) is a D2 receptor full agonist with high selectivity that plays a vital role in Parkinson's disease and restless leg syndrome.

Formula: C₁₅H₁₇N₃O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 319.31

Ref: TM-TQ0140

Sumanirole Maleate

Controlled Product

CAS: 179386-44-8

Applications Sumanirole is a high affinity D2 receptor agonist (EC50 values are between 17 and 75 nM in cell-based assays). Sumanirole displays >200-fold selectivity for the D2 receptor against other dopamine receptor subtypes (Ki values are 9.0, 1940, >2190 and >7140 for D2, D3, D4 and D1 receptors respectively). Sumanirole exhibits antiParkinsonian activity similar to Ropinirole (R641000).
References McCall, et al.: J. Pharmacol. Exp. Ther., 314 1248 (2005), Stephenson, et al.: J. Pharmacol. Exp. Ther., 314 1257 (2005),

Formula: C₁₅H₁₇N₃O₅

Color and Shape: Neat

Molecular weight: 319.313

Ref: TR-S790700

Sumanirole maleate

CAS: 179386-44-8

D2 receptor agonist; for treating Parkinson's disease and restless leg syndrome

Formula: C₁₁H₁₃N₃O·C₄H₄O₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 319.31 g/mol

Ref: 3D-FS65180