CAS 179461-52-0

Formula: C11H8FNO2S

InChI: InChI=1S/C11H8FNO2S/c12-7-1-2-9-8(4-7)6(5-13-9)3-10(16)11(14)15/h1-5,13,16H,(H,14,15)/b10-3-

InChI key: HWMQHECFXSVZGN-KMKOMSMNSA-N

SMILES: C1=CC2=C(C=C1F)C(=CN2)/C=C(/C(=O)O)\S

PD 151746

CAS: 179461-52-0

PD 151746

Formula: C₁₁H₈FNO₂S

Purity: 99%

Molecular weight: 237.25

Ref: 54-BUP06376

PD 151746

Controlled Product

CAS: 179461-52-0

Applications PD 151746 acts as a cell-permeable calpain inhibitor which induce pertussis toxin (PTx)-sensitive chemotaxis in neutrophils and human monocytes. This results in an inhibition of inflammation.
References Fujita, H. et al.: Arch. Biochem. Biophys., 513, 51 (2011);

Formula: C₁₁H₈FNO₂S

Color and Shape: Neat

Molecular weight: 237.25

Ref: TR-P217535

PD 151746

CAS: 179461-52-0

PD151746: calpain inhibitor, Ki μ-calpain=0.26μM, Ki m-calpain=5.33μM; reduces oxLDL cytotoxicity.

Formula: C₁₁H₈FNO₂S

Purity: 99.04% - ≥95%

Color and Shape: Yellow Solid

Molecular weight: 237.25

Ref: TM-T2493

PD 151746

CAS: 179461-52-0

Formula: C₁₁H₈FNO₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 237.2501

Ref: IN-DA00AB99