CAS 1795144-22-7

Formula: C18H15N5O6S2

InChI: InChI=1S/C18H15N5O6S2/c1-29-18-17(19-10-11-20-18)22-31(27,28)14-6-2-12(3-7-14)21-15(24)8-4-13-5-9-16(30-13)23(25)26/h2-11H,1H3,(H,19,22)(H,21,24)/b8-4+/i2D,3D,6D,7D

InChI key: FNPPHVLYVGMZMZ-GTQWLDGCSA-N

SMILES: [2H]C1=C(C(=C(C(=C1NC(=O)/C=C/C2=CC=C(S2)[N+](=O)[O-])[2H])[2H])S(=O)(=O)NC3=NC=CN=C3OC)[2H]

Necrosulfonamide-d4

CAS: 1795144-22-7

Necrosulfonamide-d4

Formula: C₁₈H₁₁D₄N₅O₆S₂

Purity: 99%

Molecular weight: 465.5

Ref: 54-DE3456

Necrosulfonamide-D4

CAS: 1795144-22-7

Necrosulfonamide-D4 is the deuterated form of Necrosulfonamide. Necrosulfonamide (T6904) acts as a necroptosis inhibitor by selectively targeting (MLKL). It hinders the interaction between the MLKL-RIP1-RIP3 necrosome complex and its downstream effectors. MLKL serves as a crucial substrate of RIP3 in the necrosis induction process.

Formula: C₁₈H₁₅N₅O₆S₂

Molecular weight: 465.50

Ref: TM-TMID-0800

Necrosulfonamide-d4

Controlled Product

CAS: 1795144-22-7

Applications Labelled Necrosulfonamide. Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway.
References Sun, L. et al.: Cell, 148, 213 (2012);

Formula: C₁₈H₁₁D₄N₅O₆S₂

Color and Shape: Neat

Molecular weight: 465.5

Ref: TR-N388602

Necrosulfonamide-d4

CAS: 1795144-22-7

Necrosulfonamide-d4 is a compound that plays a crucial role in various biological processes. It acts as a growth factor and is involved in the metabolism of fatty acids and glutamate. Additionally, it contributes to the synthesis of biomass and is utilized in the production of methanol. Necrosulfonamide-d4 also interacts with basic proteins and has been found to have an impact on ticagrelor, chamomile extract, acetyltransferase, xylose, sulfadiazine, chemokines, industrial applications, cellulose production, and Life Sciences research. Its diverse range of applications makes it a valuable component in many fields.

Formula: C₁₈H₁₅N₅O₆S₂

Purity: Min. 95%

Molecular weight: 465.5 g/mol

Ref: 3D-VWC14422