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CAS 179602-65-4

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Mitratapide

Description:
Mitratapide is a chemical compound that belongs to the class of drugs known as selective inhibitors of the microsomal triglyceride transfer protein (MTP). It is primarily investigated for its potential use in treating conditions related to dyslipidemia and obesity. The compound works by inhibiting the transfer of triglycerides and cholesterol to apolipoprotein B-containing lipoproteins, which can lead to reduced levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the bloodstream. Mitratapide has been studied for its effects on lipid metabolism and its ability to promote weight loss in clinical settings. Its pharmacological profile includes properties that may influence lipid absorption and metabolism, making it a candidate for therapeutic applications in metabolic disorders. As with any pharmaceutical agent, the safety, efficacy, and side effects of Mitratapide are critical considerations in its development and use. Further research is necessary to fully understand its mechanisms and potential benefits in clinical practice.
Formula:C36H41ClN8O4S
InChI:InChI=1S/C36H41ClN8O4S/c1-4-26(2)45-35(46)44(25-39-45)31-11-9-29(10-12-31)42-17-19-43(20-18-42)30-13-15-32(16-14-30)47-21-33-22-48-36(49-33,27-5-7-28(37)8-6-27)23-50-34-40-38-24-41(34)3/h5-16,24-26,33H,4,17-23H2,1-3H3/t26-,33-,36-/m1/s1
InChI key:InChIKey=HQSRVYUCBOCBLY-XOOFNSLWSA-N
SMILES:C(SC=1N(C)C=NN1)[C@@]2(O[C@H](COC3=CC=C(C=C3)N4CCN(CC4)C5=CC=C(C=C5)N6C(=O)N([C@@H](CC)C)N=C6)CO2)C7=CC=C(Cl)C=C7
Synonyms:
  • 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(4-chlorophenyl)-2-[[(4-methyl-4H-1,2,4-triazol-3-yl)thio]methyl]-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-, [2S-[2α,4α(S*)]]-
  • 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[(2S,4R)-2-(4-chlorophenyl)-2-[[(4-methyl-4H-1,2,4-triazol-3-yl)thio]methyl]-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-[(1R)-1-methylpropyl]-
  • R 103757
  • 4-[4-[4-[4-[[(2S,4R)-2-(4-Chlorophenyl)-2-[[(4-methyl-4H-1,2,4-triazol-3-yl)thio]methyl]-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-[(1R)-1-methylpropyl]-3H-1,2,4-triazol-3-one
  • Mitratapide
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