CAS 1800506-48-2

Formula: C27H32F2N8

InChI: InChI=1S/C27H32F2N8/c1-5-35-6-8-36(9-7-35)16-19-13-31-27(32-14-19)34-25-12-21(23(29)15-30-25)20-10-22(28)26-24(11-20)37(17(2)3)18(4)33-26/h10-15,17H,5-9,16H2,1-4H3,(H,30,31,32,34)

InChI key: CMOYPFUEZDEQEH-UHFFFAOYSA-N

SMILES: CCN1CCN(CC1)CC2=CN=C(N=C2)NC3=NC=C(C(=C3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F

CDK4/6-IN-2

CAS: 1800506-48-2

CDK4/6-IN-2

Formula: C₂₇H₃₂F₂N₈

Purity: ≥98%

Molecular weight: 506.59

Ref: 54-BUP00485

CDK4/6-IN-2

CAS: 1800506-48-2

CDK4/6-IN-2 是一种CDK4和CDK6抑制剂，IC50分别为 2.7 和 16 nM。

Formula: C₂₇H₃₂F₂N₈

Purity: 99.47%

Color and Shape: Solid

Molecular weight: 506.5934

Ref: TM-T10736

5-((4-Ethylpiperazin-1-yl)methyl)-N-(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyridin-2-yl)pyrimidin-2-amine

CAS: 1800506-48-2

Purity: 95%

Ref: IN-DA01V3KG

CDK4/6-IN-2

CAS: 1800506-48-2

5-((4-Ethylpiperazin-1-yl)methyl)-N-(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyridin-2-yl)pyrimidin-2-amine

Formula: C₂₇H₃₂F₂N₈

Purity: 99%

Molecular weight: 506.59

Ref: IN-DG01145523

CDK4/6-IN-2

CAS: 1800506-48-2

CDK4/6-IN-2 is an analog of a potent and selective CDK4/6 inhibitor that has shown promising anticancer activity. It works by inhibiting the activity of CDK4 and CDK6 kinases, which are involved in cell cycle progression and cancer cell growth. This inhibitor has been shown to induce apoptosis in human tumor cells, making it a potential candidate for cancer treatment. CDK4/6-IN-2 has been synthesized from urine samples of Chinese medicinal plants and has been extensively studied for its pharmacological properties. It is a highly specific protein kinase inhibitor that shows excellent potency against various types of cancer cells.

Formula: C₂₇H₃₂F₂N₈

Purity: Min. 95%

Molecular weight: 506.6 g/mol

Ref: 3D-AXC50648