CAS 1801765-04-7

Formula: C18H24ClN7OS

InChI: InChI=1S/C18H24ClN7OS/c1-10-14(20)18(9-27-10)3-6-26(7-4-18)12-8-24-17(16(22)25-12)28-11-2-5-23-15(21)13(11)19/h2,5,8,10,14H,3-4,6-7,9,20H2,1H3,(H2,21,23)(H2,22,25)/t10-,14+/m0/s1

InChI key: UCJZOKGUEJUNIO-IINYFYTJSA-N

SMILES: C[C@H]1[C@H](C2(CCN(CC2)C3=CN=C(C(=N3)N)SC4=C(C(=NC=C4)N)Cl)CO1)N

TNO155

CAS: 1801765-04-7

TNO155 inhibits SHP2 enzyme with an IC50 of 0.011 μM, potentially aiding cancer treatment.

Formula: C₁₈H₂₄ClN₇OS

Purity: 98.03% - 99.63%

Color and Shape: White Solid

Molecular weight: 421.947

Ref: TM-T13176

TNO155

CAS: 1801765-04-7

TNO155

Formula: C₁₈H₂₄ClN₇OS

Purity: 99.5%

Molecular weight: 421.95

Ref: 54-BUP08948

(3S,4S)-8-(6-Amino-5-((2-amino-3-chloropyridin-4-yl)thio)pyrazin-2-yl)-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine

CAS: 1801765-04-7

(3S,4S)-8-(6-Amino-5-((2-amino-3-chloropyridin-4-yl)thio)pyrazin-2-yl)-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine

Formula: C₁₈H₂₄ClN₇OS

Purity: 98%

Molecular weight: 421.95

Ref: IN-DG01205930

(3S,4S)-8-[6-Amino-5-[(2-amino-3-chloro-4-pyridinyl)thio]-2-pyrazinyl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine

CAS: 1801765-04-7

Purity: 98%

Color and Shape: Solid

Molecular weight: 421.95

Ref: 10-F980851

TNO155

CAS: 1801765-04-7

TNO155 is an innovative therapeutic agent, commonly classified as a small-molecule inhibitor, which is derived from rational drug design based on precision oncology principles. Its mode of action involves selective inhibition of a specific protein tyrosine phosphatase, which plays a critical role in cellular signaling pathways that are often dysregulated in cancer. This inhibition effectively disrupts aberrant signaling, thereby suppressing tumor cell proliferation and inducing apoptosis in malignant cells.

Formula: C₁₈H₂₄ClN₇OS

Purity: Min. 95%

Molecular weight: 421.9 g/mol

Ref: 3D-BT179499

(3S,4S)-8-(6-Amino-5-((2-amino-3-chloropyridin-4-yl)sulfanyl)pyrazin-2-yl)-3-methyl-2-oxa-8-azaspiro( 4.5)decan-4-amine

CAS: 1801765-04-7

Formula: C₁₈H₂₄ClN₇OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 421.9475

Ref: IN-DA01KFZR