CAS 1805789-54-1

3-Piperidinol, 4-[[[3-(1-methylethyl)-7-[(phenylmethyl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]-, hydrochloride (1:1), (3R,4R)-

Description:

3-Piperidinol, 4-[[[3-(1-methylethyl)-7-[(phenylmethyl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]-, hydrochloride (1:1), (3R,4R)- is a chemical compound characterized by its complex structure, which includes a piperidine ring and a pyrazolopyrimidine moiety. This substance is typically classified as a hydrochloride salt, indicating that it is a protonated form of the base compound, enhancing its solubility in water and stability. The presence of various functional groups, such as amines and alkyl substituents, suggests potential biological activity, possibly as a pharmaceutical agent. The stereochemistry indicated by (3R,4R) denotes specific spatial arrangements of atoms, which can significantly influence the compound's pharmacological properties. As with many compounds in medicinal chemistry, its efficacy and safety profile would depend on its interaction with biological targets, necessitating thorough investigation through in vitro and in vivo studies. The CAS number 1805789-54-1 uniquely identifies this compound in chemical databases, facilitating research and regulatory processes.

Formula: C₂₂H₃₁ClN₆O

InChI: InChI=1S/C22H30N6O.ClH/c1-15(2)18-13-26-28-21(25-11-16-6-4-3-5-7-16)10-20(27-22(18)28)24-12-17-8-9-23-14-19(17)29;/h3-7,10,13,15,17,19,23,25,29H,8-9,11-12,14H2,1-2H3,(H,24,27);1H/t17-,19+;/m1./s1

InChI key: YMNPLAHCOLEZJE-ZFNKBKEPSA-N

SMILES: CC(C)C1=C2N=C(C=C(N2N=C1)NCC3=CC=CC=C3)NC[C@H]4CCNC[C@@H]4O.Cl

Synonyms:

• ICEC0942 (CT7001)
• (3R,4R)-4-(((7-(Benzylamino)-3-isopropylpyrazolo[1,5-a]pyrimidin-5-yl)amino)methyl)piperidin-3-olhydrochloride
• 3-Piperidinol, 4-3-(1-methylethyl)-7-(phenylmethyl)aminopyrazolo1,5-apyrimidin-5-ylaminomethyl-, hydrochloride (1
• 1), (3R,4R)-
• CT7001 hydrochloride
• Samuraciclib hydrochloride
• ICEC0942;ICE C0942;ICE-C0942;CT7001;CT-7001;CT 7001
• PPDA-001 HCL SALT
• ICEC 0942 hydrochloride
• 3-Piperidinol, 4-[[[3-(1-methylethyl)-7-[(phenylmethyl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]-, hydrochloride (1:1), (3R,4R)-

Samuraciclib hydrochloride

CAS: 1805789-54-1

Samuraciclib HCl is an oral CDK7 inhibitor (IC50: 41 nM), 45-230x selective over CDK1/2/5/9, inhibiting breast cancer growth (GI50: 0.2-0.3 μM).

Formula: C₂₂H₃₁ClN₆O

Purity: 99.14% - 99.63%

Color and Shape: Solid

Molecular weight: 430.974

Ref: TM-T10898

Samuraciclib HCl

CAS: 1805789-54-1

Formula: C₂₂H₃₁ClN₆O

Purity: 99%

Color and Shape: Solid

Molecular weight: 430.9741

Ref: IN-DA01EOQ4

Samuraciclib hydrochloride

CAS: 1805789-54-1

Samuraciclib hydrochloride

Formula: C₂₂H₃₁ClN₆O

Purity: 99.5%

Molecular weight: 430.97

Ref: 54-BUP14291

Samuraciclib HCl

CAS: 1805789-54-1

(3R,4R)-4-(((7-(Benzylamino)-3-isopropylpyrazolo[1,5-a]pyrimidin-5-yl)amino)methyl)piperidin-3-ol hydrochloride

Formula: C₂₂H₃₁ClN₆O

Purity: 99%

Molecular weight: 430.97

Ref: IN-DG00796664

CT7001 Hydrochloride

Controlled Product

CAS: 1805789-54-1

Applications CT7001 Hydrochloride, is a selective CDK7 inhibitor.
References Hazel P, et al. ChemMedChem. 2017 Mar 7;12(5):372-380.;

Formula: C₂₂H₃₀N₆O·ClH

Color and Shape: Neat

Molecular weight: 430.974

Ref: TR-C831025

ICEC0942 (CT7001)

CAS: 1805789-54-1

ICEC0942 is a protein kinase inhibitor that inhibits the activity of transcription factors. It has been shown to have anticancer effects in laboratory studies and in clinical trials on patients with cancer. ICEC0942 was found to be effective at a dose of 0.3 mg/kg, which is lower than the doses typically used for chemotherapy drugs. ICEC0942 also has a low toxicity profile and does not cause DNA damage or cellular dysregulation, which are common side effects of other cancer therapies.

Formula: C₂₂H₃₁ClN₆O

Purity: Min. 95%

Molecular weight: 430.97 g/mol

Ref: 3D-FXC78954