CAS 180675-08-5

FMOC-ASP(OMPE)-OH

Description:

FMOC-ASP(OMPE)-OH, also known as 9-fluorenylmethoxycarbonyl aspartic acid with an O-methylphenyl ether (OMPE) protecting group, is a chemical compound commonly used in peptide synthesis and organic chemistry. It features a fluorenylmethoxycarbonyl (FMOC) group, which serves as a protective group for the amino functionality, allowing for selective reactions without interference from the amine. The aspartic acid component contributes to its role in peptide synthesis, providing a carboxylic acid group that can participate in coupling reactions. The OMPE group enhances the stability and solubility of the compound, making it suitable for various synthetic applications. FMOC-ASP(OMPE)-OH is typically utilized in solid-phase peptide synthesis, where the protection and deprotection of functional groups are crucial for the successful assembly of peptides. Its characteristics include good solubility in organic solvents, stability under standard laboratory conditions, and compatibility with various coupling reagents. Overall, this compound is valuable in the field of biochemistry and pharmaceutical development for constructing peptides with specific sequences and functionalities.

Formula: C₂₈H₂₇NO₇

Synonyms:

• Fmoc-Aspartic Acid(Ompe)
• N-Alpha-(9-Fluorenylmethoxycarbonyl)-L-Aspartic Acid 3-Methyl-Pent-3-Yl
• N-Alpha-(9-Fluorenylmethoxycarbonyl)-L-Aspartic Acid 3-Methylpentyl Ester
• N-Alpha-Fmoc-(O-3-Methyl-Pent-3-Yl)Aspartic Acid

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-((3-methylpentan-3-yl)oxy)-4-oxobutanoic acid

CAS: 180675-08-5

Purity: 97%

Molecular weight: 439.5079956

Ref: 10-F615571

N-Fmoc-L-aspartic acid 4-methylpentyl ester, 98%

CAS: 180675-08-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₅H₂₉NO₆

Purity: 98%

Molecular weight: 439.51

Ref: 02-H66281

Fmoc-Asp(OMpe)-OH

CAS: 180675-08-5

The OMpe (O-3-methylpent-3-yl) side chain protecting group significantly reduces aspartimide formation, an undesired side-chain reaction encountered with the repetitive piperidine treatment needed for Fmoc removal.

Formula: C₂₅H₂₉NO₆

Purity: 99.6%

Color and Shape: White

Molecular weight: 439.51

Ref: 01-4033988

L-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 4-(1-ethyl-1-methylpropyl) ester

CAS: 180675-08-5

Formula: C₂₅H₂₉NO₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 439.5009

Ref: IN-DA00227V

Fmoc-Asp(OMpe)-OH

CAS: 180675-08-5

Fmoc-Asp(OMpe)-OH

Purity: 97%

Molecular weight: 439.50g/mol

Ref: 54-OR72270

Fmoc-L-aspartic acid β-methylpentyl ester

CAS: 180675-08-5

Fmoc-L-aspartic acid b-methylpentyl ester is a solid phase synthesis of Asp(OtBu)-OH that has been synthesized by reacting aspartic acid with piperidine and methylbenzene. This synthesis has been shown to be effective at temperatures below 25°C, to minimize the formation of water, and to be resistant to treatments with strong acids or bases. The synthesis has also been optimized for the peptidyl bond formation and peptide synthesis, resulting in enhanced yields.

Formula: C₂₅H₂₉NO₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 439.5 g/mol

Ref: 3D-FF49939