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CAS 180675-08-5

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FMOC-ASP(OMPE)-OH

Description:
FMOC-ASP(OMPE)-OH, also known as 9-fluorenylmethoxycarbonyl aspartic acid with an O-methylphenyl ether (OMPE) protecting group, is a chemical compound commonly used in peptide synthesis and organic chemistry. It features a fluorenylmethoxycarbonyl (FMOC) group, which serves as a protective group for the amino functionality, allowing for selective reactions without interference from the amine. The aspartic acid component contributes to its role in peptide synthesis, providing a carboxylic acid group that can participate in coupling reactions. The OMPE group enhances the stability and solubility of the compound, making it suitable for various synthetic applications. FMOC-ASP(OMPE)-OH is typically utilized in solid-phase peptide synthesis, where the protection and deprotection of functional groups are crucial for the successful assembly of peptides. Its characteristics include good solubility in organic solvents, stability under standard laboratory conditions, and compatibility with various coupling reagents. Overall, this compound is valuable in the field of biochemistry and pharmaceutical development for constructing peptides with specific sequences and functionalities.
Formula:C28H27NO7
InChI:InChI=1S/C25H29NO6/c1-4-25(3,5-2)32-22(27)14-21(23(28)29)26-24(30)31-15-20-18-12-8-6-10-16(18)17-11-7-9-13-19(17)20/h6-13,20-21H,4-5,14-15H2,1-3H3,(H,26,30)(H,28,29)/t21-/m0/s1
InChI key:SYGKUYKLHYQKPL-NRFANRHFSA-N
SMILES:CCC(C)(CC)OC(=O)C[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Synonyms:
  • Fmoc-Aspartic Acid(Ompe)
  • N-Alpha-(9-Fluorenylmethoxycarbonyl)-L-Aspartic Acid 3-Methyl-Pent-3-Yl
  • N-Alpha-(9-Fluorenylmethoxycarbonyl)-L-Aspartic Acid 3-Methylpentyl Ester
  • N-Alpha-Fmoc-(O-3-Methyl-Pent-3-Yl)Aspartic Acid
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