CAS 181931-30-6

Miconazole IMpurity H

Description:

Miconazole Impurity H, with the CAS number 181931-30-6, is a chemical compound associated with the antifungal agent miconazole, which is commonly used in the treatment of various fungal infections. As an impurity, it may arise during the synthesis or degradation of miconazole and can affect the purity and efficacy of pharmaceutical formulations. The characteristics of Miconazole Impurity H include its molecular structure, which is related to the miconazole framework, and it may exhibit similar physical properties such as solubility in organic solvents. Impurities like this can influence the pharmacological profile of the main compound, potentially altering its therapeutic effects or safety profile. Analytical methods such as high-performance liquid chromatography (HPLC) are typically employed to identify and quantify impurities in pharmaceutical products. Understanding the characteristics of such impurities is crucial for quality control in drug manufacturing, ensuring that the final product meets regulatory standards for safety and efficacy.

Formula: C₁₈H₁₆Cl₂N₂O

InChI: InChI=1S/C18H16Cl2N2O/c19-15-6-7-16(17(20)10-15)18(11-22-9-8-21-13-22)23-12-14-4-2-1-3-5-14/h1-10,13,18H,11-12H2

InChI key: CSENVQMNWOFZIZ-UHFFFAOYSA-N

SMILES: C1=CC=C(C=C1)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl

Synonyms:

• MicozoleEPImpurityHHCl
• 1-[(2RS)-2-Benzyloxy-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
• Miconazole EP Impurity H
• Miconazole Nitrate EP Impurity H
• Miconazole EP IMP H
• Miconazole IMpurity H
• Miconazole Impurity 8(Miconazole EP Impurity H)
• 1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-(phenylmethoxy)ethyl]-
• Miconazole EP Impurity H HCl

Benzyl Miconazole

CAS: 181931-30-6

Compounds containing an unfused imidazole ring, whether or not hydrogenated, in the structure, nesoi

Formula: C₁₈H₁₆Cl₂N₂O

Color and Shape: Light Yellow Oil

Molecular weight: 346.06397

Ref: 45-1A18740

Miconazole EP Impurity H HCl

CAS: 181931-30-6, 203264-09-9

Formula: C₁₈H₁₆Cl₂N₂O·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 347.24 36.46

Ref: 4Z-M-735

Miconazole Impurity H

Controlled Product

CAS: 181931-30-6

Impurity Miconazole EP Impurity H
Applications Miconazole Impurity H (Miconazole EP Impurity H), is the impurity of Miconazole (M342500), which is an imidazole antifungal agent, that is applied topically to the skin or to mucus membranes for the treatment of fungal infections.
References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, et al.: Arch. Dermatol., 102, 428 (1970), Heel, R.C., et al.: Drugs, 19, 7 (1980),

Formula: C₁₈H₁₆Cl₂N₂O

Color and Shape: Neat

Molecular weight: 347.24

Ref: TR-M342490

Miconazole EP Impurity H

CAS: 181931-30-6

Formula: C₁₈H₁₆Cl₂N₂O

Molecular weight: 347.2

Ref: BE-RMCM184030

Miconazole Impurity H-d7

Controlled Product

CAS: 181931-30-6

Formula: C₁₈D₇H₉Cl₂N₂O

Color and Shape: Neat

Molecular weight: 354.282

Ref: TR-M342492

Miconazole impurity H

CAS: 181931-30-6

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Formula: C₁₈H₁₆Cl₂N₂O

Purity: Min. 95%

Molecular weight: 347.2 g/mol

Ref: 3D-GHA93130

Miconazole EP Impurity H

CAS: 181931-30-6

Formula: C₁₈H₁₆Cl₂N₂O

Molecular weight: 347.24

Ref: ST-EA-CP-M46008