CAS 182349-12-8: Rupatadine fumarate

Description: Rupatadine fumarate is an antihistamine medication primarily used for the treatment of allergic conditions such as allergic rhinitis and urticaria. It functions as a selective antagonist of the H1 histamine receptor, which helps alleviate symptoms associated with allergies, including sneezing, itching, and runny nose. Additionally, rupatadine exhibits anti-inflammatory properties, which may contribute to its therapeutic effects. The substance is typically administered orally and is known for its relatively long duration of action, allowing for once-daily dosing. Rupatadine fumarate is a salt form of rupatadine, enhancing its solubility and bioavailability. The compound is generally well-tolerated, with a side effect profile that may include drowsiness, headache, and dry mouth, although these effects are typically mild. As with any medication, it is important for patients to consult healthcare professionals for appropriate usage and to discuss potential interactions with other drugs. Overall, rupatadine fumarate represents a valuable option in the management of allergic symptoms.

Formula: C₂₆H₂₆ClN₃·C₄H₄O₄

InChI: InChI=1S/C26H26ClN3.C4H4O4/c1-18-13-19(16-28-15-18)17-30-11-8-20(9-12-30)25-24-7-6-23(27)14-22(24)5-4-21-3-2-10-29-26(21)25;5-3(6)1-2-4(7)8/h2-3,6-7,10,13-16H,4-5,8-9,11-12,17H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

InChI key: InChIKey=JYBLCDXVHQWMSU-WLHGVMLRSA-N

SMILES: O=C(O)C=CC(=O)O.ClC=1C=CC2=C(C1)CCC=3C=CC=NC3C2=C4CCN(CC=5C=NC=C(C5)C)CC4

Synonyms:

• 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridinyl)methyl]-4-piperidinylidene]-, (2E)-2-butenedioate (1:1)
• 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridinyl)methyl]-4-piperidinylidene]-, (E)-2-butenedioate (1:1)
• 8-Chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridyl)methyl]-4-piperidylidene]-5H-benzo[5,6]cyclohepta[1,2-b]pyridine fumarate
• Rupatadine fumarate

Rupatadine fumarate CRS

CAS: 182349-12-8

• Formula: C₃₀H₃₀ClN₃O₄
• Molecular weight: 532.0299

5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridinyl)methyl]-4-piperidinylidene]-, (2E)-2-butenedioate (1:1)

CAS: 182349-12-8

• Formula: C₃₀H₃₀ClN₃O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 532.0299

Rupatadine Fumarate

CAS: 182349-12-8

Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 …

• Formula: C₂₆H₂₆ClN₃·C₄H₄O₄
• Purity: 99.86%
• Color and Shape: White Or Almost-White Powder
• Molecular weight: 532.03

Rupatadine Fumarate

CAS: 182349-12-8

• Formula: C₂₆H₂₆ClN₃·C₄H₄O₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 415.97 116.07

Rupatadine Fumarate

CAS: 182349-12-8

• Purity: 95%
• Molecular weight: 532.03g/mol

Rupatadine Fumarate

CAS: 182349-12-8

• Formula: C₂₆H₂₆ClN₃·C₄H₄O₄
• Color and Shape: Neat
• Molecular weight: 532.03

Rupatadine fumarate

CAS: 182349-12-8

Dual antagonist of histamine H1 receptors and platelet-activating factor

• Formula: C₂₆H₂₆ClN₃•C₄H₄O₄
• Purity: Min. 97.5 Area-%
• Color and Shape: Powder
• Molecular weight: 532.03 g/mol

Rupatadine fumarate - Bio-X ™

CAS: 182349-12-8

Rupatadine is a dual histamine H1 receptor and platelet activating factor antagonist that is used …

• Formula: C₃₀H₃₀ClN₃O₄
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 532.03 g/mol