CAS 182349-12-8

Rupatadine fumarate

Description:

Rupatadine fumarate is an antihistamine medication primarily used for the treatment of allergic conditions such as allergic rhinitis and urticaria. It functions as a selective antagonist of the H1 histamine receptor, which helps alleviate symptoms associated with allergies, including sneezing, itching, and runny nose. Additionally, rupatadine exhibits anti-inflammatory properties, which may contribute to its therapeutic effects. The substance is typically administered orally and is known for its relatively long duration of action, allowing for once-daily dosing. Rupatadine fumarate is a salt form of rupatadine, enhancing its solubility and bioavailability. The compound is generally well-tolerated, with a side effect profile that may include drowsiness, headache, and dry mouth, although these effects are typically mild. As with any medication, it is important for patients to consult healthcare professionals for appropriate usage and to discuss potential interactions with other drugs. Overall, rupatadine fumarate represents a valuable option in the management of allergic symptoms.

Formula: C₂₆H₂₆ClN₃·C₄H₄O₄

InChI: InChI=1S/C26H26ClN3.C4H4O4/c1-18-13-19(16-28-15-18)17-30-11-8-20(9-12-30)25-24-7-6-23(27)14-22(24)5-4-21-3-2-10-29-26(21)25;5-3(6)1-2-4(7)8/h2-3,6-7,10,13-16H,4-5,8-9,11-12,17H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

InChI key: InChIKey=JYBLCDXVHQWMSU-WLHGVMLRSA-N

SMILES: ClC=1C=C2C(C(C=3C(CC2)=CC=CN3)=C4CCN(CC=5C=C(C)C=NC5)CC4)=CC1.C(=C/C(O)=O)\C(O)=O

Synonyms:

• 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridinyl)methyl]-4-piperidinylidene]-, (2E)-2-butenedioate (1:1)
• 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridinyl)methyl]-4-piperidinylidene]-, (E)-2-butenedioate (1:1)
• 8-Chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridyl)methyl]-4-piperidylidene]-5H-benzo[5,6]cyclohepta[1,2-b]pyridine fumarate
• Rupatadine fumarate

RUPATADINE FUMARATE CRS

CAS: 182349-12-8

RUPATADINE FUMARATE CRS

Formula: C₃₀H₃₀ClN₃O₄

Molecular weight: 532.0299

Ref: 41-Y0001922

Rupatadine Fumarate

CAS: 182349-12-8

Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM.

Formula: C₂₆H₂₆ClN₃·C₄H₄O₄

Purity: 99.86%

Color and Shape: White Or Almost-White Powder

Molecular weight: 532.03

Ref: TM-T6242

(2E)-but-2-enedioic acid; 13-chloro-2-{1-[(5-methylpyridin-3-yl)methyl]piperidin-4-ylidene}-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaene

CAS: 182349-12-8

Formula: C₃₀H₃₀ClN₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 532.0299

Ref: IN-DA0023OM

Rupatadine Fumarate

CAS: 182349-12-8

Rupatadine Fumarate

Formula: C₂₆H₂₆ClN₃C₄H₄O₄

Purity: 98%

Molecular weight: 532.03

Ref: 54-OR1029855

Rupatadine Fumarate

CAS: 182349-12-8

Rupatadine Fumarate

Formula: C₂₆H₂₆ClN₃·C₄H₄O₄

Purity: ≥98%

Molecular weight: 532.03

Ref: 54-BUP11945

Rupatadine Fumarate

CAS: 182349-12-8

Formula: C₂₆H₂₆ClN₃·C₄H₄O₄

Color and Shape: White To Off-White Solid

Molecular weight: 415.97 116.07

Ref: 4Z-R-421

Rupatadine Fumarate

CAS: 182349-12-8

Formula: C₂₆H₂₆ClN₃·C₄H₄O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 532.04

Ref: 3B-R0325

Rupatadine Fumarate

CAS: 182349-12-8

8-Chloro-11-(1-((5-methylpyridin-3-yl)methyl)piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine fumarate

Formula: C₃₀H₃₀ClN₃O₄

Purity: 98%

Molecular weight: 532.03

Ref: IN-DG161088

Rupatadine Fumarate

CAS: 182349-12-8

Formula: C₂₆H₂₆ClN₃C₄H₄O₄

Molecular weight: 415.97 : 116.07

Ref: ST-EA-CP-R4002

Rupatadine Fumarate

Controlled Product

CAS: 182349-12-8

Formula: C₂₆H₂₆ClN₃·C₄H₄O₄

Color and Shape: Neat

Molecular weight: 532.03

Ref: TR-R701650

Rupatadine fumarate

CAS: 182349-12-8

Dual antagonist of histamine H1 receptors and platelet-activating factor

Formula: C₂₆H₂₆ClN₃•C₄H₄O₄

Purity: Min. 97.5 Area-%

Color and Shape: Powder

Molecular weight: 532.03 g/mol

Ref: 3D-FR27769

Rupatadine fumarate - Bio-X ™

CAS: 182349-12-8

Rupatadine is a dual histamine H1 receptor and platelet activating factor antagonist that is used for the treatment of allergic rhinitis. It can also be used for the treatment of chronic spontaneous urticaria. This drug inhibits the H1 receptor and the platelet activating factor receptor from carrying out their roles resulting in a reduction in the symptoms of allergic rhinitis.

Formula: C₃₀H₃₀ClN₃O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 532.03 g/mol

Ref: 3D-BR164385

Rupatadine fumarate

CAS: 182349-12-8

Purity: ≥99%

Molecular weight: 531.192

Ref: 10-F556527