CAS 182410-00-0

β-Cyclodextrin, sulfobutyl ethers, sodium salts

Description:

β-Cyclodextrin, sulfobutyl ethers, sodium salts, commonly referred to as sulfobutyl ether β-cyclodextrin (SBE-β-CD), is a modified cyclodextrin that enhances the solubility and stability of various compounds, particularly hydrophobic drugs. This compound features a cyclic oligosaccharide structure composed of seven glucose units, with sulfobutyl ether groups introduced to improve its water solubility and biocompatibility. The sodium salt form enhances its ionic properties, making it suitable for pharmaceutical applications, particularly in drug formulation and delivery systems. SBE-β-CD can form inclusion complexes with a wide range of guest molecules, which can improve the bioavailability and therapeutic efficacy of poorly soluble drugs. Additionally, it exhibits low toxicity and is generally recognized as safe (GRAS) for use in food and pharmaceutical products. Its ability to stabilize sensitive compounds and enhance their solubility makes it a valuable excipient in various formulations, including oral, injectable, and topical preparations. Overall, SBE-β-CD is a versatile compound with significant applications in the pharmaceutical and food industries.

Formula: Unspecified

Synonyms:

• Betadex Sulfobutyl Ether Sodium
• Captisol
• SBE7-beta-CD
• Sodium sulfobutylether β-cyclodextrin
• Sulfobutyl ether-beta-cyclodextrin sodium salt
• β-Cyclodextrin, sulfobutyl ethers, sodium salts

SULFOBUTYLBETADEX SODIUM CRS

CAS: 182410-00-0

SULFOBUTYLBETADEX SODIUM CRS

Ref: 41-Y0001998

Betadex Sulfobutyl Ether Sodium

CAS: 182410-00-0

Sugars, chemically pure, other than sucrose, lactose, maltose, glucose and fructose; sugar ethers and sugar esters, and their salts, nesoi

Formula: C₄₂H₇₀nO₃₅(C₄H₈SO₃Na)n

Color and Shape: White Off-White Powder

Molecular weight: 1451.287

Ref: 45-1065550

Sulfobutylated β-cyclodextrin sodium salt (DS~6)

CAS: 182410-00-0

Sulfobutylated β-cyclodextrin sodium salt (DS~6)

Color and Shape: Solid-Powder

Ref: 54-BICY1025

β-Cyclodextrin, sulfobutyl ethers, sodium salts

CAS: 182410-00-0

Formula: C₇₀H₁₁₉Na₇O₅₆S₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 2242.0436

Ref: IN-DA0023V4

Sulfobutylated β-cyclodextrin sodium salt (DS~4)

CAS: 182410-00-0

Sulfobutylated β-cyclodextrin sodium salt (DS~4)

Formula: C₇₀H₁₁₉O₅₆S₇·7Na

Molecular weight: 2242.04364

Ref: 54-BICY1024

Sodium Sulfobutyl Ether β-Cyclodextrin

CAS: 182410-00-0

Sodium Sulfobutyl Ether β-Cyclodextrin

Purity: >98%

Color and Shape: Solid

Ref: 54-BICY1082

Sulfobutyl ether β-cyclodextrin sodium

CAS: 182410-00-0

Formula: C₇₀H₁₁₉Na₇O₅₆S₇

Purity: 95.0 - 105.0 %

Color and Shape: White to off-white powder

Molecular weight: 2242.05

Ref: 7W-GP8988

Sulfobutylated β-cyclodextrin sodium salt (DS~10)

CAS: 182410-00-0

Sulfobutylated β-cyclodextrin sodium salt (DS~10)

Purity: 98%

Color and Shape: Solid

Molecular weight: 0.00g/mol

Ref: 54-BICY1026

SBE-β-CD

CAS: 182410-00-0

SBE-β-CD

Purity: 98%

Ref: IN-DG243603

ß-Cyclodextrin Sulfobutyl Ethers Sodium Salts

CAS: 182410-00-0

Ref: 4Z-S-082089

SBE-β-CD

CAS: 182410-00-0

SBE-β-CD (Sulfobutylether-β-Cyclodextrin) is a β-cyclodextrin derivative with a sodium sulfonate salt separated from the lipophilic cavity by a butyl ether

Formula: C₂₃H₂₅NO₄S

Purity: 98% - ≥98%

Color and Shape: White Solid

Molecular weight: 411.52

Ref: TM-T16858

b-Cyclodextrin Sulfobutyl Ethers, Sodium Salts

Controlled Product

CAS: 182410-00-0

Applications β-Cyclodextrin with sulfobutyl ether groups and sodium ions substituted along the length of the molecule. β-Cyclodextrin is a cyclic oligosaccharide produced from starch via enzymatic conversion. β-Cyclodextrin is commonly used to produce HPLC columns allowing chiral enantiomers separation.
References Motoyama, A. et al.: J. Pharmac. Biomed. Anal., 28, 97 (2002); Nakamura, N. et al. Biotechnol. Bioeng., 19, 87 (1977); Riddle, L. A. et al.: J. Chrom. Sci., 45, 330 (2007);

Formula: C₄₂H₇₀O₃₅•xNa•x(C₄H₉O₃S)

Color and Shape: Neat

Molecular weight: 1451.3

Ref: TR-C987845

b-Cyclodextrin sulfobutyl ether sodium salt

CAS: 182410-00-0

Beta-cyclodextrin sulfobutyl ether is an excipient compound incorporating a chemically modified cyclodextrin with a structure that optimizes the solubility and stability of active pharmaceuticals and their properties. It is a highly water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules and therefore reduce drug toxicity and haemolysis as well as control drug release rate. Its complexing properties also make it suitable for masking unpleasant odors and tastes of pharmaceutical products. It is used as an excipient in injection, oral, nasal, and eye medication.

Formula: C₇₀H₁₁₉Na₇O₅₆S₇

Purity: 95 To 105%

Color and Shape: White Powder

Molecular weight: 2,242.05 g/mol

Ref: 3D-OC59560

SBE-beta-CD

CAS: 182410-00-0

β-cyclodextrin sulfobutyl ether (SBE-beta-CD) is an excipient compound incorporating a chemically modified cyclodextrin with a structure that optimizes the solubility and stability of active pharmaceuticals and their properties. It is a highly water-soluble anionic cyclodextrin derivative. SBE-beta-CD can easily form non-covalent inclusion complexes with drug molecules and therefore reduce drug toxicity and haemolysis as well as control drug release rate. The complexing properties of beta- dex sulfobutyl ether also make it suitable for masking unpleasant odors and tastes of pharmaceutical products. It is used as an excipient in injection, oral, nasal, and eye medication.

Formula: C₇₀H₁₁₉Na₇O₅₆S₇

Purity: Min. 98%

Color and Shape: White Powder

Molecular weight: 2,242.05 g/mol

Ref: 3D-OC15979

ß-Cyclodextrin Sulfobutyl Ethers Sodium Salts

CAS: 182410-00-0

Ref: ST-EA-CP-S32051