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CAS 182410-00-0

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β-Cyclodextrin, sulfobutyl ethers, sodium salts

Description:
β-Cyclodextrin, sulfobutyl ethers, sodium salts, commonly referred to as sulfobutyl ether β-cyclodextrin (SBE-β-CD), is a modified cyclodextrin that enhances the solubility and stability of various compounds, particularly hydrophobic drugs. This compound features a cyclic oligosaccharide structure composed of seven glucose units, with sulfobutyl ether groups introduced to improve its water solubility and biocompatibility. The sodium salt form enhances its ionic properties, making it suitable for pharmaceutical applications, particularly in drug formulation and delivery systems. SBE-β-CD can form inclusion complexes with a wide range of guest molecules, which can improve the bioavailability and therapeutic efficacy of poorly soluble drugs. Additionally, it exhibits low toxicity and is generally recognized as safe (GRAS) for use in food and pharmaceutical products. Its ability to stabilize sensitive compounds and enhance their solubility makes it a valuable excipient in various formulations, including oral, injectable, and topical preparations. Overall, SBE-β-CD is a versatile compound with significant applications in the pharmaceutical and food industries.
Formula:Unspecified
Synonyms:
  • Betadex Sulfobutyl Ether Sodium
  • Captisol
  • SBE7-beta-CD
  • Sodium sulfobutylether β-cyclodextrin
  • Sulfobutyl ether-beta-cyclodextrin sodium salt
  • β-Cyclodextrin, sulfobutyl ethers, sodium salts
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