CAS 184179-08-6

Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid)

Description:

Ac-Asp-Glu-Val-Asp-aldehyde, also known as a pseudo acid, is a synthetic peptide derivative characterized by its specific amino acid sequence, which includes aspartic acid (Asp), glutamic acid (Glu), and valine (Val), along with an aldehyde functional group. This compound is notable for its potential applications in biochemical research and drug development, particularly in the study of peptide interactions and modifications. The presence of the aldehyde group suggests reactivity that can facilitate further chemical transformations or conjugations. The peptide structure may influence its biological activity, stability, and solubility, making it a subject of interest in the fields of medicinal chemistry and biochemistry. Additionally, the compound's CAS number, 184179-08-6, allows for precise identification and retrieval of information in chemical databases. Overall, Ac-Asp-Glu-Val-Asp-aldehyde represents a unique molecular entity with potential implications in various scientific investigations.

Formula: C₂₀H₃₀N₄O₁₁

Synonyms:

• Ac-Devd-Cho

Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid)

CAS: 184179-08-6

Ac-DEVD-CHO is a potent inhibitor of the poly(ADP-ribose) polymerase (PARP) cleavage by caspase-3 (IC₅₀ = 0.2 nM). PARP cleavage occurs at the onset of apoptosis. The peptide aldehyde was able to attenuate apoptotic events in vitro (IC₅₀ = 10 to 100 nM).

Formula: C₂₀H₃₀N₄O₁₁

Purity: 98.3%

Color and Shape: White Lyophilisate

Molecular weight: 502.48

Ref: 01-4026022

Ac-Asp-Glu-Val-Asp-H (aldehyde)

CAS: 184179-08-6

Ac-Asp-Glu-Val-Asp-H (aldehyde) is a peptide that belongs to the group of ligands. It has been used as an inhibitor of ion channels and as an antibody for cell biology research. Ac-Asp-Glu-Val-Asp-H (aldehyde) is a potent activator of the class IB metabotropic glutamate receptors and has been shown to inhibit the activity of the Na+/K+ ATPase pump in rat brain synaptosomes. This peptide also binds to beta 2 adrenergic receptors with high affinity, but does not activate them.

Formula: C₂₀H₃₀N₄O₁₁

Purity: Min. 95%

Molecular weight: 502.47 g/mol

Ref: 3D-IAP-3172-V

Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid)

CAS: 184179-08-6

Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid) is a pro-apoptotic protein that belongs to the group of pseudo acids. It is able to induce apoptosis. Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid) can induce neuronal death by activating caspases and apoptosis pathway, which are involved in the process of programmed cell death. This protein also has anti-inflammatory properties, which may be due to its ability to inhibit cyclase activity. Ac-Asp-Glu-Val-Asp (pseudo acid) has been shown to be present at physiological levels in the brain and heart, where it may play an important role in maintaining cell viability.

Formula: C₂₀H₃₀N₄O₁₁

Purity: Min. 95%

Molecular weight: 502.47 g/mol

Ref: 3D-FA108687