CAS 18449-41-7

madasiatic acid

Description:

Madasiatic acid, with the CAS number 18449-41-7, is a naturally occurring triterpenoid compound primarily derived from the plant species of the genus *Madasiaticus*. This compound is characterized by its complex molecular structure, which typically includes multiple rings and functional groups, contributing to its biological activity. Madasiatic acid exhibits various pharmacological properties, including anti-inflammatory, antioxidant, and potential anticancer effects, making it of interest in medicinal chemistry and natural product research. It is often studied for its role in traditional medicine and its potential therapeutic applications. The compound is generally soluble in organic solvents, and its stability can be influenced by environmental factors such as pH and temperature. Research into madasiatic acid continues to explore its mechanisms of action and potential uses in pharmaceuticals, highlighting the importance of natural products in drug discovery and development.

Formula: C₃₀H₄₈O₆

InChI: InChI=1/C30H48O6/c1-16-9-10-30(25(35)36)12-11-28(5)18(22(30)17(16)2)7-8-21-26(3)13-20(33)24(34)27(4,15-31)23(26)19(32)14-29(21,28)6/h7,16-17,19-24,31-34H,8-15H2,1-6H3,(H,35,36)/t16-,17+,19-,20-,21?,22+,23?,24+,26-,27+,28-,29-,30+/m1/s1

InChI key: InChIKey=PRAUVHZJPXOEIF-AOLYGAPISA-N

SMILES: C[C@@]12[C@@]3([C@](C)([C@@]4(C)C(=CC3)[C@]5([C@@](C(O)=O)(CC4)CC[C@@H](C)[C@@H]5C)[H])C[C@@H](O)[C@]1([C@@](CO)(C)[C@@H](O)[C@H](O)C2)[H])[H]

Synonyms:

• (1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-Trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
• (2Alpha,3Beta,5Xi,6Beta,9Xi)-2,3,6,23-Tetrahydroxyurs-12-En-28-Oic Acid
• (2Alpha,3Beta,6Beta)-2,3,6,23-Tetrahydroxyurs-12-En-28-Oic Acid
• (2α,3β,4α,6β)-2,3,6,23-Tetrahydroxyurs-12-en-28-oic acid
• 2,3,6,23-Tetrahydroxyurs-12-En-28-Oic Acid
• 2α,3β,6β,23-Tetrahydroxy-urs-12-en-28-oic acid
• 6β-Hydroxyasiatic acid
• Brahmic acid
• Cid 12073158
• Madecassic acid
• Nsc 88135
• Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2alpha,3beta,4alpha,6beta)-
• Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,4α,6β)-
• Urs-12-en-28-oic acid, 2α,3β,6β,23-tetrahydroxy-
• Hydroxy asiaticoside
• 6-Hydroxyasiatic acid
• 6BETA-HYDROXYASIATIC ACID
• Madecassic acid, froM Centella asiatica
• Madecassic Acid (97%)
• (1S,2R,4aS,6aS,6bR,8R,9R,10R,11R,12aR)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
• (2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oic acid
• (1S,2R,4aS,6aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bR)-8,10,11-trihydroxy -9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,1 1,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
• Madecassic acid, 98%, from Centella asiatica (L.) Urb.
• MADECASSIC ACID(P)
• Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2.alpha.,3.beta.,4.alpha.,6.beta.)-
• Brahmic acid 18449-41-7
• 2α,3β,6β,23-Tetrahydroxyurs-12-en-28-oic acid

Urs-​12-​en-​28-​oic acid, 2,​3,​6,​23-​tetrahydroxy-​, (2α,​3β,​4α,​6β)​-

CAS: 18449-41-7

Formula: C₃₀H₄₈O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 504.6985

Ref: IN-DA00I1H4

Madecassic acid

CAS: 18449-41-7

Madecassic acid

Purity: ≥98%

Molecular weight: 504.7g/mol

Ref: 54-BUP10594

Madecassic acid

CAS: 18449-41-7

Formula: C₁₄H₁₁ClN₂O

Purity: ≥ 98.0%

Color and Shape: White to light pink solid

Molecular weight: 258.70

Ref: 7W-GP1826

Madecassic Acid

CAS: 18449-41-7

Formula: C₃₀H₄₈O₆

Molecular weight: 504.71

Ref: 4Z-M-276002

Madecassic acid

CAS: 18449-41-7

Formula: C₃₀H₄₈O₆

Purity: 95%~99%

Molecular weight: 504.708

Ref: BP-BP0910

Madecassic acid

CAS: 18449-41-7

Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.

Formula: C₃₀H₄₈O₆

Purity: 98.80% - 99.69%

Color and Shape: Solid

Molecular weight: 504.70

Ref: TM-T2758

Madecassic acid

CAS: 18449-41-7

Carboxylic acid with alcohol function

Formula: C₃₀H₄₈O₆

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 504.71

Ref: 5G-80229

Madecassic Acid

Controlled Product

CAS: 18449-41-7

Applications Madecassic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Madecassic Acid displays anti-inflammatory properties as a result of iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-kappaB activation in RAW 264.7 macrophage cells. Madecassic Acid is found in cosmetic products due to its skin-protective activities.
References Wonh, J.H. et al.: Planta Med., 76, 251 (2010); Kwon, M.C. et al.: J. Biotechnol., 157, 100 (2012); Loiseau, A. et al.: Cosm. Toil., 115, 63 (2000);

Formula: C₃₀H₄₈O₆

Purity: 97%

Color and Shape: Neat

Molecular weight: 504.70

Ref: TR-M107500

Madecassic acid

Controlled Product

CAS: 18449-41-7

Madecassic acid is a triterpenoid compound, which is a natural chemical constituent of Centella asiatica, commonly known as Gotu Kola. This source is a perennial herbaceous plant belonging to the Apiaceae family, widely distributed in tropical and subtropical countries. Madecassic acid acts primarily through its anti-inflammatory and antioxidant mechanisms. It modulates inflammatory responses by inhibiting the activation of NF-κB signaling pathways and reducing the production of pro-inflammatory cytokines. Additionally, it contributes to cellular protection by scavenging reactive oxygen species.

Formula: C₃₀H₄₈O₆

Purity: Min. 95%

Molecular weight: 504.7 g/mol

Ref: 3D-FM73960