CAS 18456-03-6

(-)-Bakkenolide D

Formula: C₂₁H₂₈O₆S

InChI: InChI=1S/C21H28O6S/c1-12-6-7-15(27-16(23)8-9-28-5)17-18(26-14(3)22)21(11-20(12,17)4)13(2)10-25-19(21)24/h8-9,12,15,17-18H,2,6-7,10-11H2,1,3-5H3/b9-8-/t12-,15-,17+,18+,20+,21+/m0/s1

InChI key: InChIKey=LWHLMCCRIWZBQO-PDSBHGERSA-N

SMILES: O(C(C)=O)[C@H]1[C@@]2(C[C@@]3(C)[C@@]1([C@@H](OC(/C=C\SC)=O)CC[C@@H]3C)[H])C(=C)COC2=O

Synonyms:

• 2-Propenoic acid, 3-(methylthio)-, 3′-(acetyloxy)decahydro-7′,7′a-dimethyl-4-methylene-2-oxospiro[furan-3(2H),2′-[2H]inden]-4′-yl ester, [2′R-[2′α,3′α,3′aα,4′β(Z),7′α,7′aα]]-
• Acrylic acid, 3-(methylthio)-, 7′-ester with 3′a,4,4′,5,5′,6′,7′,7′aβ-octahydro-1′β,7′α-dihydroxy-3′aβ,4′β-dimethyl-4-methylenespiro[furan-3(2H),2′-indan]-2-one acetate, (Z)-
• Spiro[furan-3(2H),2′-indan]-2-one, 3′a,4,4′,5,5′,6,7,7′aβ-octahydro-1′β,7′α-dihydroxy-3′aβ,4′β-dimethyl-4-methylene-, 1′-acetate 3-(methylthio)acrylate, (Z)-
• Bakkenolide D
• 2-Propenoic acid, 3-(methylthio)-, (2′R,3′R,3′aR,4′S,7′S,7′aR)-3′-(acetyloxy)decahydro-7′,7′a-dimethyl-4-methylene-2-oxospiro[furan-3(2H),2′-[2H]inden]-4′-yl ester, (2Z)-

Bakkenolide D

CAS: 18456-03-6

Bakkenolide D

Formula: C₂₁H₂₈O₆S

Purity: ≥98%

Molecular weight: 408.51

Ref: 54-OR1116351

Bakkenolide D

CAS: 18456-03-6

Bakkenolide D inhibits histamine-induced trachea contractions, showing anti-allergic properties.

Formula: C₂₁H₂₈O₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 408.51

Ref: TM-TN3483

Bakkenolide D

CAS: 18456-03-6

Formula: C₂₁H₂₈O₆S

Purity: 95%~99%

Molecular weight: 408.509

Ref: BP-SBP03743

Bakkenolide D

CAS: 18456-03-6

Bakkenolide D is a sesquiterpene lactone, which is a bioactive compound isolated from the plant Petasites japonicus, commonly known as Japanese butterbur. It functions through various modes of action, primarily by modulating inflammatory pathways in biological systems. Research indicates that Bakkenolide D inhibits the activation of nuclear factor-kappa B (NF-κB), a transcription factor that plays a critical role in regulating immune responses and inflammation. By suppressing NF-κB, Bakkenolide D can reduce the expression of pro-inflammatory cytokines and other mediators, leading to its potential anti-inflammatory effects.

Formula: C₂₁H₂₈O₆S

Purity: Min. 95%

Molecular weight: 408.5 g/mol

Ref: 3D-TAA45603