CAS 184582-62-5

3-(2,7-dimethoxyacridin-9-ylthio)propan-1-amine

Description:

3-(2,7-Dimethoxyacridin-9-ylthio)propan-1-amine, identified by its CAS number 184582-62-5, is a chemical compound that features a unique structure combining an acridine moiety with a propan-1-amine group. This compound is characterized by the presence of two methoxy groups at the 2 and 7 positions of the acridine ring, which can influence its solubility and reactivity. The thioether linkage (with sulfur) enhances its potential for biological activity, making it of interest in medicinal chemistry. The amine functional group suggests that it may participate in hydrogen bonding and can act as a nucleophile in various chemical reactions. Its structural features may contribute to specific interactions with biological targets, potentially leading to applications in pharmaceuticals or as a probe in biochemical research. Overall, the compound's unique combination of functional groups and structural characteristics positions it as a subject of interest for further study in both synthetic and medicinal chemistry contexts.

Synonyms:

• 2,7-Dimethoxy-9-(3'-aminopropyl)thioacridine

LDN-192960

CAS: 184582-62-5

LDN-192960

Purity: ≥98%

Molecular weight: 328.43g/mol

Ref: 54-BUP08828

3-[(2,7-Dimethoxyacridin-9-yl)sulfanyl]propan-1-amine

CAS: 184582-62-5

3-[(2,7-Dimethoxyacridin-9-yl)sulfanyl]propan-1-amine

Purity: 98%

Color and Shape: Yellow Solid

Molecular weight: 328.43g/mol

Ref: 54-OR305567

LDN-192960

CAS: 184582-62-5

LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).

Formula: C₁₈H₂₀N₂O₂S

Purity: 99.01% - 99.51%

Color and Shape: Solid

Molecular weight: 328.43

Ref: TM-TQ0111

LDN-192960 dihydrochloride

CAS: 184582-62-5

LDN-192960 is a serine/threonine-protein kinase inhibitor that targets the catalytic domain of the enzyme. LDN-192960 inhibits cancer cell growth by inhibiting mitotic activity and histone phosphorylation. LDN-192960 also has been shown to inhibit the catalytic activity of serine/threonine-protein kinases, which are involved in many cellular processes including regulation of transcription, translation, apoptosis, and tumorigenesis. LDN-192960 binds to specific residues on the protein's surface and prevents phosphorylation of these residues, leading to inhibition of its catalytic activity. This drug has high inhibitory potency against mitotic serine/threonine-protein kinases and is currently being researched for its potential use in treating cancer.

Formula: C₁₈H₂₀N₂O₂S·2HCl

Purity: Min. 95%

Molecular weight: 401.35 g/mol

Ref: 3D-JHA58262