CAS 1847-24-1: Flucloxacillin sodium

Description: Flucloxacillin sodium is a semisynthetic antibiotic belonging to the penicillin class, primarily used to treat infections caused by Gram-positive bacteria, particularly Staphylococcus aureus. It is characterized by its beta-lactam structure, which is essential for its antibacterial activity. The sodium salt form enhances its solubility in water, facilitating intravenous administration. Flucloxacillin is resistant to penicillinase, an enzyme produced by certain bacteria that can inactivate other penicillins, making it effective against penicillin-resistant strains. It is typically administered for skin infections, respiratory tract infections, and bone infections. The drug is absorbed well when taken orally, although its bioavailability can be affected by food. Common side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, liver toxicity. Flucloxacillin sodium is generally contraindicated in individuals with a known allergy to penicillins or cephalosporins. As with all antibiotics, it is crucial to complete the prescribed course to prevent the development of antibiotic resistance.

Formula: C₁₉H₁₇ClFN₃O₅S·Na

InChI: InChI=1S/C19H17ClFN3O5S.Na/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);/t13-,14+,17-;/m1./s1

InChI key: InChIKey=PWDULVAXRLDWLM-SLINCCQESA-N

SMILES: [Na].O=C(O)C1N2C(=O)C(NC(=O)C=3C(=NOC3C)C=4C(F)=CC=CC4Cl)C2SC1(C)C

Synonyms:

• (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-
• 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, (2S-(2-alpha,5-alpha,6-beta))-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-, sodium salt
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-(2α,5α,6β)]-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:1), (2S,5R,6R)-
• 5-Methyl-3-(2-chloro-6-fluorophenyl)-4-isoxazolylpenicillin sodium
• 6-({[3-(2-Chloro-6-Fluorophenyl)-5-Methyl-1,2-Oxazol-4-Yl]Carbonyl}Amino)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid
• Floxacillin Na salt
• Floxacillin sodium
• Floxapen
• Floxapen sodium
• Fluclox
• Flucloxacillin sodium salt
• Mfi-Pc
• Monosodium flucloxacillin
• Nsc 277175
• Sodium (2S-(2alpha,5alpha,6beta))-6-(((3-(2-chloro-6-fluorophenyl)-5-methylisoxazol-4-yl)carbonyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate
• Sodium 6-({[3-(2-Chloro-6-Fluorophenyl)-5-Methylisoxazol-4-Yl]Carbonyl}Amino)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
• Sodium [3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]penicillin
• Sodium flucloxacillin
• Stafopen sodium salt
• Staphylex
• Staphylex Sodium salt
• sodium (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• Flucloxacillin sodium

Flucloxacillin sodium

CAS: 1847-24-1

Used in clinical in vitro tests known as antimicrobial susceptibility tests. It is used in …

• Formula: C₁₉H₁₆ClFN₃NaO₅S
• Molecular weight: 475.85

Flucloxacillin sodium

CAS: 1847-24-1

• Formula: C₁₉H₁₆ClFN₃NaO₅S
• Purity: 94.6%
• Color and Shape: Off-White
• Molecular weight: 475.03809

Flucloxacillin sodium RS

CAS: 1847-24-1

• Formula: C₁₉H₁₆ClFN₃NaO₅S
• Molecular weight: 475.8536

Flucloxacillin sodium CRS

CAS: 1847-24-1

• Formula: C₁₉H₁₆ClFN₃NaO₅S
• Color and Shape: Crystalline Powder. White. Powder.
• Molecular weight: 475.8536

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-

CAS: 1847-24-1

• Formula: C₁₉H₁₆ClFN₃NaO₅S
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 475.8536

(2S,5R,6R)-6-(3-(2-Chloro-6-Fluorophenyl)-5-Methylisoxazole-4-Carboxamido)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid,Sodium Salt

CAS: 1847-24-1

• Purity: 95%
• Molecular weight: 475.85g/mol

Flucloxacillin Sodium Salt

CAS: 1847-24-1

• Formula: C₁₉H₁₆ClFN₃O₅S·Na
• Molecular weight: 452.86 22.99

Flucloxacillin Sodium

CAS: 1847-24-1

• Formula: C₁₉H₁₆ClFN₃NaO₅S
• Purity: >95.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 475.85

Flucloxacillin sodium

CAS: 1847-24-1

• Formula: C₁₉H₁₆ClFN₃O₅S·Na
• Color and Shape: Neat
• Molecular weight: 475.85

Flucloxacillin Sodium Hydrate

CAS: 1847-24-134214-51-2

• Color and Shape: Neat

Flucloxacillin sodium

CAS: 1847-24-1

Flucloxacillin sodium (floxacillin sodium) is a highly active antibiotic against Gram-negative and Gram-positive bacteria.

• Formula: C₁₉H₁₆ClFN₃NaO₅S
• Purity: 99.27%
• Color and Shape: White Solid
• Molecular weight: 475.85

Flucloxacillin sodium salt

CAS: 1847-24-1

• Formula: C₁₉H₁₆ClFN₃O₅S·Na
• Purity: ≥ 95.0%
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 475.85

Flucloxacillin-13C4 Sodium

CAS: 1847-24-1

Applications Labelled analogue of Flucloxacillin, a semisynthetic penicillin. References Markovich, M. et al.: Antibiot. Med. …

• Formula: C₁₅C₄H₁₆ClFN₃NaO₅S
• Color and Shape: White To Off-White
• Molecular weight: 479.82

Flucloxacillin Sodium

CAS: 1847-24-1

Applications Flucloxacillin, a new semisynthetic penicillin. References Markovich, M., et al.: Antibiot. Med. Biotekhnol., 31, …

• Formula: C₁₉H₁₆ClFN₃O₅S·Na
• Color and Shape: Off-White
• Molecular weight: 475.85

Flucloxacillin sodium

CAS: 1847-24-1

Please enquire for more information about Flucloxacillin sodium including the price, delivery time and more …

• Formula: C₁₉H₁₆ClFN₃NaO₅S
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 475.85 g/mol