CAS 185066-37-9

Formula: C31H39NO2

InChI: InChI=1S/C31H39NO2/c1-24(2)25-15-17-26(18-16-25)30(33)14-9-21-32-22-19-29(20-23-32)31(34,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-13,15-18,24,29-30,33-34H,9,14,19-23H2,1-2H3

InChI key: FZSQPQGERLSIOR-UHFFFAOYSA-N

SMILES: CC(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O

FEXOFENADINE IMPURITY C CRS

CAS: 185066-37-9

FEXOFENADINE IMPURITY C CRS

Ref: 41-Y0000753

Decarboxy Fexofenadine

CAS: 185066-37-9

Decarboxy Fexofenadine

Formula: C₃₁H₃₉NO₂

Purity: 98%

Molecular weight: 457.65

Ref: 54-OR1105737

Fexofenadine EP Impurity C

CAS: 185066-37-9

Formula: C₃₁H₃₉NO₂

Color and Shape: White To Off-White Solid

Molecular weight: 457.66

Ref: 4Z-F-047

Fexofenadine EP Impurity C

Controlled Product

CAS: 185066-37-9

Formula: C₃₁H₃₉NO₂

Color and Shape: Neat

Molecular weight: 457.65

Ref: 86-MM0507.03

Decarboxy Fexofenadine

Controlled Product

CAS: 185066-37-9

Impurity Fexofenadine EP Impurity C
Applications Decarboxy Fexofenadine is a photodegradation product of Fexofenadine (F322490), the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist.
References Holzer, M., et al.: Molec., 13, 1081 (2008); Breier, A.R., et al.: J. Pharma. Biomed. Anal., 46, 250 (2008); Pratt, E., et al.: Diabet Med., 18, 515 (2001); Mizutani, N., et al.: J. Pharmacol. Sci., 93, 437 (2003)

Formula: C₃₁H₃₉NO₂

Color and Shape: Neat

Molecular weight: 457.65

Ref: TR-D220750

Fexofenadine EP Impurity C

CAS: 185066-37-9

Formula: C₃₁H₃₉NO₂

Molecular weight: 457.7

Ref: ST-EA-CP-F13003

Decarboxy Fexofenadine-d3

Controlled Product

CAS: 185066-37-9

Formula: C₃₁D₃H₃₆NO₂

Color and Shape: Neat

Molecular weight: 460.665

Ref: TR-D220752

Fexofenadine EP impurity C

CAS: 185066-37-9

Fexofenadine is a nonsedating antihistamine that has been shown to be effective in the treatment of allergic reactions. Impurity C is a carboxylate impurity that can be found in Fexofenadine EP. It has been shown to have metal hydroxide impurities, which may affect the flow rate of this drug. The chromatographic science and chromatographic methods used for the analysis of Fexofenadine EP are important for determining the purity and effectiveness of this drug. The diode-array detector (DAD) used in this method is able to detect impurities in Fexofenadine EP, such as impurity C. This method also has cardiotoxic effects, which may result from decarboxylated impurity C.

Formula: C₃₁H₃₉NO₂

Purity: Min. 95%

Molecular weight: 457.65 g/mol

Ref: 3D-FF171822