CAS 185099-67-6

8-Boc-8-azabicyclo[3.2.1]octan-3-one

Description:

8-Boc-8-azabicyclo[3.2.1]octan-3-one is a bicyclic compound characterized by its unique structural framework, which includes a bicyclo[3.2.1]octane core with a nitrogen atom incorporated into the ring system. The "Boc" (tert-butoxycarbonyl) group is a common protecting group in organic synthesis, particularly for amines, indicating that the nitrogen atom is likely part of an amine functional group. This compound typically exhibits properties such as moderate solubility in organic solvents, and its reactivity can be influenced by the presence of the Boc group, which can be removed under acidic conditions to reveal the free amine. The bicyclic structure contributes to its rigidity and potential for specific interactions in biological systems, making it of interest in medicinal chemistry and drug design. Additionally, the presence of the carbonyl group suggests potential for further chemical transformations, such as nucleophilic additions or reductions. Overall, 8-Boc-8-azabicyclo[3.2.1]octan-3-one is a versatile compound with applications in synthetic organic chemistry and pharmaceutical research.

Formula: C₁₂H₁₉NO₃

InChI: InChI=1/C12H19NO3/c1-12(2,3)16-11(15)13-8-4-5-9(13)7-10(14)6-8/h8-9H,4-7H2,1-3H3

InChI key: MENILFUADYEXNU-UHFFFAOYSA-N

SMILES: CC(C)(C)OC(=O)N1C2CCC1CC(=O)C2

Synonyms:

• Tert-butyl(1R,5S)-3-oxo-8-Azabicyclo[3.2.1]Octane-8-Carboxylate
• 8-Azabicyclo[3.2.1]octan-3-one, N-BOC protected
• Tert-butyl 3-oxo-8-AZABICYCLO[3.2.1]Octane-8-Carboxylate
• Rarechem Em Wb 0263
• BOC-Nortropinone
• Boc-Ntp
• Tert-butyl3-oxo-8-Azabicyclo[3.2.1]Octane-8-Carboxylate
• Rarechememwb0263
• N-(tert-Butoxycarbonyl)nortropinone
• 8-Azabicyclo[3.2.1]octan-3-one,N-BOCprotected
• N-Boc-Nororopinone
• N-Boc-Nortropinone
• 3-Oxo-8-azabicyclo[3.2.1]octane-8-carboxylic Acid 1,1-Dimethylethyl Ester
• N-Boc-nortropin-3-one

N-(tert-Butoxycarbonyl)nortropinone

CAS: 185099-67-6

Formula: C₁₂H₁₉NO₃

Purity: >98.0%(HPLC)(qNMR)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 225.29

Ref: 3B-B3401

8-Azabicyclo[3.2.1]octan-3-one, N-BOC protected

CAS: 185099-67-6

8-Azabicyclo[3.2.1]octan-3-one, N-BOC protected

Formula: C₁₂H₁₉NO₃

Purity: 98%

Color and Shape: Off-white Solid-Crystals

Molecular weight: 225.28416

Ref: 54-OR12337

Nortropinone 100 µg/mL in Acetonitrile

Controlled Product

CAS: 185099-67-6

Formula: C₁₂H₁₉NO₃

Color and Shape: Single Solution

Molecular weight: 225.28

Ref: 04-A10899000AL-100

tert-Butyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate

CAS: 185099-67-6

Formula: C₁₂H₁₉NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 225.2842

Ref: IN-DA003SU3

tert-Butyl 3-oxo-8-azaicyclo[3.2.1]octane-8-carboxylate

CAS: 185099-67-6

Formula: C₁₂H₁₉NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 225.288

Ref: 10-F047015

N-Boc-nortropinone

CAS: 185099-67-6

tert-Butyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate

Formula: C₁₂H₁₉NO₃

Purity: 98%

Molecular weight: 225.28

Ref: IN-DG14249

N-Boc-nortropinone

Controlled Product

CAS: 185099-67-6

Applications A 8-azabicyclo[3.2.1]octane derivative useful as opioid receptor modulator.
References Blier, P., et al.: J. Clin. Psychiat., 59, 16 (1998), Dunlop, J., et al.: J. Pharmacol. Toxicol., 40, 47 (1998), Takeuchi, K., et all.: Bioorg. Med. Chem. Lett., 13, 3939 (2003), Mewshaw, R., et al.: J. Med. Chem., 47, 3823 (2004),

Formula: C₁₂H₁₉NO₃

Color and Shape: Neat

Molecular weight: 225.28

Ref: TR-B658750