CAS 18559-94-9

Salbutamol

Description:

Salbutamol, also known as albuterol in some regions, is a selective beta-2 adrenergic agonist primarily used as a bronchodilator in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Its chemical formula is C13H21NO3, and it features a phenolic hydroxyl group, which contributes to its pharmacological activity. Salbutamol works by stimulating beta-2 adrenergic receptors in the smooth muscle of the airways, leading to relaxation and dilation of bronchial passages, thereby improving airflow and alleviating symptoms of bronchospasm. The substance is typically administered via inhalation, though oral and intravenous forms are also available. Salbutamol has a relatively short half-life, necessitating multiple doses for sustained effect. It is generally well-tolerated, but potential side effects may include tremors, palpitations, and headaches. As a widely used medication, salbutamol is included in essential medicine lists and is subject to regulations regarding its use in sports due to its performance-enhancing potential.

Formula: C₁₃H₂₁NO₃

InChI: InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3

InChI key: InChIKey=NDAUXUAQIAJITI-UHFFFAOYSA-N

SMILES: C(CNC(C)(C)C)(O)C1=CC(CO)=C(O)C=C1

Synonyms:

• (.+-.)-Albuterol
• (.+-.)-Salbutamol
• 1,3-Benzenedimethanol, α¹-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-
• 1-(tert-Butylaminomethyl)-4-hydroxy-m-xylene-α1,α3-diol
• 1-(tert-Butylaminomethyl)-4-hydroxy-m-xylene-α¹,α³-diol
• 2-(tert-Butylamino)-1-[(4-hydroxy-3-hydroxymethyl)phenyl]ethanol
• 4-Hydroxy-3-(hydroxymethyl)-α-[[(1,1-dimethylethyl)amino]methyl]benzenemethanol
• <span class="text-smallcaps">DL</span>-N-tert-Butyl-2(4-hydroxy-3-hydroxymethylphenyl)2-hydroxyethylamine
• Ah 3365
• Airomir
• DL-N-tert-Butyl-2(4-hydroxy-3-hydroxymethylphenyl)2-hydroxyethylamine
• Eolene
• Etinoline
• ProAir HFA
• Proventil HFA
• Proventil Inhaler
• Sabumol
• Salamol EB
• Salbiar
• Saventol
• Spreor
• Sultanol
• Sultanol N
• Ventalin Inhaler
• Ventolin
• Ventoline
• Volmax
• dl-Albuterol
• dl-Salbutamol
• m-Xylene α,α'-diol, α-[(tert-butylamino)methyl]-4-hydroxy-
• m-Xylene-α,α'-diol, α1-[(tert-butylamino)methyl]-4-hydroxy-
• m-Xylene-α,α′-diol, α¹-[(tert-butylamino)methyl]-4-hydroxy-
• α1-tert-Butylaminomethyl-4-hydroxy-m-xylene-α1,α3-diol
• α¹-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol
• α¹-tert-Butylaminomethyl-4-hydroxy-m-xylene-α¹,α³-diol
• α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol

d,l-Salbutamol, 1mg/ml in Ethanol

CAS: 18559-94-9

Color and Shape: Single Solution

Ref: LP-SAL-117-FB-1LE

Salbutamol

CAS: 18559-94-9

Salbutamol

Formula: C₁₃H₂₁NO₃

Purity: 99.8%

Color and Shape: Off-White

Molecular weight: 239.15214

Ref: 47-451

SALBUTAMOL FOR PEAK IDENTIFICATION CRS

CAS: 18559-94-9

SALBUTAMOL FOR PEAK IDENTIFICATION CRS

Color and Shape: Added Modified

Ref: 41-Y0002386

SALBUTAMOL RS

CAS: 18559-94-9

SALBUTAMOL RS

Formula: C₁₃H₂₁NO₃

Color and Shape: Added Modified

Molecular weight: 239.3107

Ref: 41-ICRS47064

SALBUTAMOL CRS

CAS: 18559-94-9

SALBUTAMOL CRS

Formula: C₁₃H₂₁NO₃

Color and Shape: Added Modified

Molecular weight: 239.3107

Ref: 41-S0100000

Albuterol

CAS: 18559-94-9

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₁₃H₂₁NO₃

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 239.15214

Ref: 45-1012600

Salbutamol

CAS: 18559-94-9

Salbutamol (Albuterol) stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3', 5'-adenosine monophosphate (cAMP).

Formula: C₁₃H₂₁NO₃

Purity: 91.59% - 99.9%

Color and Shape: White To Off-White Crystalline Solid Solid

Molecular weight: 239.31

Ref: TM-T1139

Salbutamol (Albuterol)

CAS: 18559-94-9

Formula: C₁₃H₂₁NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 239.32

Ref: 4Z-S-171

Salbutamol

CAS: 18559-94-9

Salbutamol

Color and Shape: Powder

Molecular weight: 239.31g/mol

Ref: 54-BIS7017

Salbutamol

CAS: 18559-94-9

Formula: C₁₃H₂₁NO₃

Purity: 98.0 - 101.0 % (dried basis)

Color and Shape: White to off-white powder

Molecular weight: 239.31

Ref: 7W-GP7722

(±)-Albuterol-d9 (tert-butyl-d9)

CAS: 1173021-73-2, 18559-94-9

Purity: 98 atom % D

Molecular weight: 248.37

Ref: 3U-D7928

(±)-Albuterol-d3 (3-hydroxymethyl-d2; alpha-d1)

CAS: 1219798-60-3, 18559-94-9

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 242.33

Ref: 3U-D5921

Salbutamol 100 µg/mL in Acetonitrile

CAS: 18559-94-9

Formula: C₁₃H₂₁NO₃

Color and Shape: Single Solution

Molecular weight: 239.31

Ref: 04-XA16903000AL

Salbutamol

CAS: 18559-94-9

Formula: C₁₃H₂₁NO₃

Color and Shape: Neat

Molecular weight: 239.31

Ref: 04-C16903000

d,l-Salbutamol

CAS: 18559-94-9

Color and Shape: Neat

Ref: LP-SAL-117-FB-10

rac Albuterol

Controlled Product

CAS: 18559-94-9

Applications rac Albuterol is a β2-adrenoceptor agonist. Bronchodilator; tocolytic. This compound is a contaminant of emerging concern (CECs).
References Miyagawa, N., et al.: Biol. Pharm. Bull., 31, 2260 (2008), Gonzalez-Munoz, C., et al.: Eur. J. Pharmacol., 607, 151 (2009), Kern, C., et al.: J. Med. Chem., 52, 1773 (2009),

Formula: C₁₃H₂₁NO₃

Color and Shape: White

Molecular weight: 239.31

Ref: TR-A514501

(±)-Salbutamol

Controlled Product

CAS: 18559-94-9

Salbutamol is a bronchodilator with selective beta-2 receptor activity. It is used to prevent and treat asthma and other respiratory disorders. Salbutamol has been shown to improve lung function in children with asthma and may be effective in the treatment of chronic obstructive pulmonary disease (COPD). The cardiac effects of salbutamol are related to its ability to increase blood flow through the lungs, which reduces the workload of the heart. Salbutamol also has an effect on maternal blood flow and may have some anti-inflammatory properties. Salbutamol has been shown to inhibit the transfection of DNA into cells by benzalkonium chloride, a chemical that is commonly used as a preservative in laboratory experiments. Salbutamol also inhibits eosinophil cationic protein production, which may be due to its ability to inhibit transcriptional activation of this protein or its ability to alter gene expression at post-transcriptional levels.

Formula: C₁₃H₂₁NO₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 239.31 g/mol

Ref: 3D-FA61527

Albuterol-13C6

Controlled Product

CAS: 18559-94-9

Formula: C₆C₇H₂₁NO₃

Color and Shape: Neat

Molecular weight: 245.267

Ref: TR-A514504

Salbutamol Impurity O Sulfate Salt

Controlled Product

CAS: 18559-94-9

Formula: (C₁₅H₂₅NO₃)·(H₂SO₄)

Color and Shape: Neat

Molecular weight: 632.81

Ref: TR-S085555

(±)-Salbutamol

Controlled Product

CAS: 18559-94-9

(±)-Salbutamol is a racemic mixture of a beta-2 adrenergic agonist, which is synthetically derived. This compound functions primarily by selectively stimulating beta-2 adrenergic receptors, which are predominantly located on the smooth muscle cells lining the airways. The activation of these receptors leads to the relaxation of bronchial muscle tissue, resulting in bronchodilation and improved airflow.

Formula: C₁₃H₂₁NO₃

Molecular weight: 239.31 g/mol

Ref: 3D-Q-201695