CAS 18559-94-9: Salbutamol
Description:Salbutamol, also known as albuterol in some regions, is a selective beta-2 adrenergic agonist primarily used as a bronchodilator in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Its chemical formula is C13H21NO3, and it features a phenolic hydroxyl group, which contributes to its pharmacological activity. Salbutamol works by stimulating beta-2 adrenergic receptors in the smooth muscle of the airways, leading to relaxation and dilation of bronchial passages, thereby improving airflow and alleviating symptoms of bronchospasm. The substance is typically administered via inhalation, though oral and intravenous forms are also available. Salbutamol has a relatively short half-life, necessitating multiple doses for sustained effect. It is generally well-tolerated, but potential side effects may include tremors, palpitations, and headaches. As a widely used medication, salbutamol is included in essential medicine lists and is subject to regulations regarding its use in sports due to its performance-enhancing potential.
Formula:C13H21NO3
InChI:InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3
InChI key:InChIKey=NDAUXUAQIAJITI-UHFFFAOYSA-N
SMILES:OC1=CC=C(C=C1CO)C(O)CNC(C)(C)C
- Synonyms:
- (.+-.)-Albuterol
- (.+-.)-Salbutamol
- 1,3-Benzenedimethanol, α<sup>1</sup>-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-
- 1-(tert-Butylaminomethyl)-4-hydroxy-m-xylene-α1,α3-diol
- 1-(tert-Butylaminomethyl)-4-hydroxy-m-xylene-α<sup>1</sup>,α<sup>3</sup>-diol
- 2-(tert-Butylamino)-1-[(4-hydroxy-3-hydroxymethyl)phenyl]ethanol
- 4-Hydroxy-3-(hydroxymethyl)-α-[[(1,1-dimethylethyl)amino]methyl]benzenemethanol
- <span class="text-smallcaps">DL</span>-N-tert-Butyl-2(4-hydroxy-3-hydroxymethylphenyl)2-hydroxyethylamine
- Ah 3365
- Airomir
- See more synonyms
- DL-N-tert-Butyl-2(4-hydroxy-3-hydroxymethylphenyl)2-hydroxyethylamine
- Eolene
- Etinoline
- ProAir HFA
- Proventil HFA
- Proventil Inhaler
- Sabumol
- Salamol EB
- Salbiar
- Saventol
- Spreor
- Sultanol
- Sultanol N
- Ventalin Inhaler
- Ventolin
- Ventoline
- Volmax
- dl-Albuterol
- dl-Salbutamol
- m-Xylene α,α'-diol, α-[(tert-butylamino)methyl]-4-hydroxy-
- m-Xylene-α,α'-diol, α1-[(tert-butylamino)methyl]-4-hydroxy-
- m-Xylene-α,α′-diol, α<sup>1</sup>-[(tert-butylamino)methyl]-4-hydroxy-
- α1-tert-Butylaminomethyl-4-hydroxy-m-xylene-α1,α3-diol
- α<sup>1</sup>-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol
- α<sup>1</sup>-tert-Butylaminomethyl-4-hydroxy-m-xylene-α<sup>1</sup>,α<sup>3</sup>-diol
- α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol
- 1,3-Benzenedimethanol, α1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-