CAS 186611-52-9

IC 261

Description:

IC 261, with the CAS number 186611-52-9, is a chemical compound that belongs to the class of small molecules known for their potential applications in various fields, including medicinal chemistry and biochemistry. It is characterized by its specific molecular structure, which typically includes functional groups that contribute to its biological activity. IC 261 is known to act as a selective inhibitor of certain kinases, which are enzymes that play crucial roles in cell signaling and regulation. This inhibition can affect various cellular processes, including proliferation and apoptosis, making IC 261 a subject of interest in cancer research and therapeutic development. The compound is usually studied in vitro and in vivo to evaluate its efficacy and safety profiles. Additionally, its solubility, stability, and reactivity are important characteristics that influence its application in research and potential clinical settings. As with any chemical substance, proper handling and safety protocols should be followed when working with IC 261 in laboratory environments.

Formula: C₁₈H₁₇NO₄

Synonyms:

• SU5607, 1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one
• IC261, >98%
• (E)-3-(2,4,6-trimethoxybenzylidene)indolin-2-one
• IC261 - CAS 186611-52-9 - Calbiochem
• 1,3-Dihydro-3-[(2,4,6-triMethoxyphenyl)Methylene]-2H-indol-2-one, SU5607
• 3-(2,4,6-Ttrimethoxybenzylidene)indolin-2-one
• CS-1551
• IC-261(SU-5607)
• SU-5607 IC 261
• IC261;SU5607;IC 261;SU 5607

IC261

CAS: 186611-52-9

IC261

Formula: C₁₈H₁₇NO₄

Purity: ≥98%

Molecular weight: 311.33

Ref: 54-BUP10605

3-(2,4,6-Ttrimethoxybenzylidene)Indolin-2-One

CAS: 186611-52-9

3-(2,4,6-Ttrimethoxybenzylidene)Indolin-2-One

Formula: C₁₈H₁₇NO₄

Purity: 98%

Molecular weight: 311.33

Ref: 54-OR1010629

IC 261

CAS: 186611-52-9

Formula: C₁₈H₁₇NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 311.3319

Ref: IN-DA00ABO2

IC 261

CAS: 186611-52-9

Formula: C₁₈H₁₇NO₄

Molecular weight: 311.33

Ref: 7W-GK3051

IC 261

CAS: 186611-52-9

Formula: C₁₈H₁₇NO₄

Purity: >98.0%(HPLC)

Color and Shape: White to Yellow powder to crystal

Molecular weight: 311.34

Ref: 3B-I1077

IC261

CAS: 186611-52-9

IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.

Formula: C₁₈H₁₇NO₄

Purity: 98.77% - 99.91%

Color and Shape: Solid

Molecular weight: 311.33

Ref: TM-T2440

IC261

CAS: 186611-52-9

IC261 is a small molecule inhibitor of protein kinase activity. It has been shown to inhibit the proliferation of human leukemia HL-60 cells with minimal toxicity in vitro. IC261 inhibits protein synthesis by affecting the transport of proteins into the cell nuclei and inhibiting phosphorylation of proteins. IC261 also reduces cancer cell survival by inhibiting epidermal growth factor receptor signaling, which may be due to its ability to inhibit protein kinases.

Formula: C₁₈H₁₇NO₄

Purity: Min. 95%

Molecular weight: 311.33 g/mol

Ref: 3D-LHA61152