CAS 186763-78-0

Ginsenoside Rg5

Description:

Ginsenoside Rg5 is a triterpenoid saponin derived from ginseng, specifically from the Panax species. It is one of the many ginsenosides, which are bioactive compounds known for their potential health benefits. Ginsenoside Rg5 is characterized by its complex molecular structure, which includes a steroid-like backbone with various sugar moieties attached. This compound is recognized for its pharmacological properties, including anti-inflammatory, antioxidant, and neuroprotective effects. Research suggests that ginsenoside Rg5 may play a role in enhancing cognitive function and exhibiting anti-cancer properties, although further studies are needed to fully understand its mechanisms of action and therapeutic potential. Additionally, ginsenosides like Rg5 are often studied for their ability to modulate various biological pathways, making them of interest in both traditional medicine and modern pharmacology. As with many natural compounds, the bioavailability and efficacy of ginsenoside Rg5 can be influenced by factors such as formulation and dosage.

Formula: C₄₂H₇₀O₁₂

InChI: InChI=1S/C42H70O12/c1-21(2)10-9-11-22(3)23-12-16-42(8)30(23)24(45)18-28-40(6)15-14-29(39(4,5)27(40)13-17-41(28,42)7)53-38-36(34(49)32(47)26(20-44)52-38)54-37-35(50)33(48)31(46)25(19-43)51-37/h10-11,23-38,43-50H,9,12-20H2,1-8H3/b22-11+/t23-,24-,25-,26-,27+,28-,29+,30+,31-,32-,33+,34+,35-,36-,37+,38+,40+,41-,42-/m1/s1

InChI key: InChIKey=NJUXRKMKOFXMRX-RNCAKNGISA-N

SMILES: C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O[C@H]4[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@@H](CO)O4)CC3)[H])(C[C@@H](O)[C@]6([C@@]2(C)CC[C@@H]6\C(=C\CC=C(C)C)\C)[H])[H]

Synonyms:

• (3β,12β,20E)-12-Hydroxydammara-20(22),24-dien-3-yl 2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranoside
• (8xi,9xi,12alpha,13xi,14beta,17beta)-17-[(1E)-1,5-dimethylhexa-1,4-dien-1-yl]-12-hydroxy-4,4,7,10,14-pentamethylgonan-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
• G-Rg5
• Ginsenoside Rg5E
• Ginsenoside Rg₅
• beta-D-Glucopyranoside, (3beta,12beta,20E)-12-hydroxydammara-20(22),24-dien-3-yl 2-O-beta-D-glucopyranosyl-
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,12β,20E)-12-hydroxydammara-20(22),24-dien-3-yl 2-O-β-<smallcap>D</span>-glucopyranosyl-
• Ginsenoside Rg5
• β-D-Glucopyranoside, (3β,12β,20E)-12-hydroxydammara-20(22),24-dien-3-yl 2-O-β-D-glucopyranosyl-
• (3β,12β,20E)-12-Hydroxydammara-20(22),24-dien-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

Ginsenoside Rg5

CAS: 186763-78-0

Ginsenoside Rg5

Formula: C₄₂H₇₀O₁₂

Purity: 99.5%

Molecular weight: 767.0

Ref: 54-BUP03373

Ginsenoside Rg5

CAS: 186763-78-0

Formula: C₄₂H₇₀O₁₂

Molecular weight: 947.15

Ref: 7W-GX7952

Ginsenoside Rg5 (Standard)

CAS: 186763-78-0

Ginsenoside Rg5 (Standard) is a ginsenoside reference standard with anti-inflammatory activity.

Formula: C₄₂H₇₀O₁₂

Color and Shape: Solid

Molecular weight: 766.998

Ref: TM-TMSM-2699

Ginsenoside Rg5

CAS: 186763-78-0

Ginsenoside Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasculature, it can ameliorate lung inflammation possibly by inhibiting the binding of LPS to toll-like receptor (TLR)-4 on macrophages. Ginsenoside Rg5 blocks cell cycle of SK-HEP-1 cells at the Gl/S transition phase by down-regulating cyclin E-dependent kinase activity and that the down-regulation of cyclin E-dependent kinase activity is caused mainly by induced CDK2 inhibitor, p21Cip/WAF1 and decreased levels of cyclin E.

Formula: C₄₂H₇₀O₁₂

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 767.01

Ref: BP-BP1651

Ginsenoside Rg5

CAS: 186763-78-0

(2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-4,5-Dihydroxy-2-(((3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-((E)-6-methylhepta-2,5-dien-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Formula: C₄₂H₇₀O₁₂

Purity: 99%

Molecular weight: 767.0

Ref: IN-DG630488

Ginsenoside Rg5

CAS: 186763-78-0

Formula: C₄₂H₇₀O₁₂

Molecular weight: 767.01

Ref: 4Z-G-157018

Ginsenoside Rg5

CAS: 186763-78-0

Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.

Formula: C₄₂H₇₀O₁₂

Purity: 98% - 99.65%

Color and Shape: White Solid

Molecular weight: 766.998

Ref: TM-T6S1487

Ginsenoside Rg5

CAS: 186763-78-0

Formula: C₄₂H₇₀O₁₂

Molecular weight: 767.0

Ref: BE-RMCG062018

Ginsenoside Rg5

CAS: 186763-78-0

Formula: C₄₂H₇₀O₁₂

Molecular weight: 767.0

Ref: BE-RMT16707