CAS 186901-48-4

cortistatin-14

Description:

Cortistatin-14 is a peptide derived from the cortistatin family, which is known for its neuropeptide properties and potential roles in various physiological processes. This particular peptide consists of 14 amino acids and is characterized by its unique sequence that contributes to its biological activity. Cortistatin-14 is primarily recognized for its involvement in modulating sleep patterns, neuroprotection, and influencing the immune response. It exhibits a high affinity for certain receptors in the brain, which may play a role in regulating neurotransmitter release and neuronal excitability. Additionally, cortistatin-14 has been studied for its potential therapeutic applications in conditions such as sleep disorders and neurodegenerative diseases. Its stability and bioactivity make it a subject of interest in pharmacological research. As with many peptides, its synthesis can be achieved through solid-phase peptide synthesis techniques, allowing for the production of this compound for further study and potential clinical applications.

Formula: C₈₁H₁₁₃N₁₉O₁₉S₂

InChI: InChI=1S/C81H113N19O19S2/c1-46(103)67-80(117)95-59(38-49-24-9-4-10-25-49)73(110)96-62(42-101)76(113)97-63(43-102)77(114)99-65(79(116)90-56(81(118)119)30-15-18-34-84)45-121-120-44-64(98-68(105)53-31-19-35-86-53)78(115)89-54(28-13-16-32-82)69(106)94-61(40-66(85)104)75(112)92-57(36-47-20-5-2-6-21-47)71(108)91-58(37-48-22-7-3-8-23-48)72(109)93-60(39-50-41-87-52-27-12-11-26-51(50)52)74(111)88-55(70(107)100-67)29-14-17-33-83/h2-12,20-27,41,46,53-65,67,86-87,101-103H,13-19,28-40,42-45,82-84H2,1H3,(H2,85,104)(H,88,111)(H,89,115)(H,90,116)(H,91,108)(H,92,112)(H,93,109)(H,94,106)(H,95,117)(H,96,110)(H,97,113)(H,98,105)(H,99,114)(H,100,107)(H,118,119)/t46-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65+,67+/m1/s1

InChI key: DDRPLNQJNRBRNY-WYYADCIBSA-N

SMILES: C[C@H]([C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)[C@@H]6CCCN6)C(=O)N[C@@H](CCCCN)C(=O)O)CO)CO)CC7=CC=CC=C7)O

Cortistatin 14

CAS: 186901-48-4

For cellular and molecular biology applications

Color and Shape: Lyophilized powder, White

Ref: 02-J66255

Cortistatin-14

CAS: 186901-48-4

Cortistatin-14

Formula: C₈₁H₁₁₄N₂₀O₁₈S₂

Purity: ≥98%

Molecular weight: 1720.03

Ref: 54-BUP21974

Cortistatin-14

CAS: 186901-48-4

Formula: C₈₁H₁₁₄N₂₀O₁₈S₂

Purity: 97%

Molecular weight: 1720.0251

Ref: IN-DA00AP90

Cortistatin-14

CAS: 186901-48-4

Cortistatin-14, a neuropeptide structurally similar to growth inhibitor-14, is used to study sepsis-induced cognitive impairment.

Formula: C₈₁H₁₁₄N₂₀O₁₈S₂

Purity: 98.06% - 98.23%

Color and Shape: Solid

Molecular weight: 1720.03

Ref: TM-TP1570