CAS 187164-19-8
:Luliconazole
Description:
Luliconazole is an antifungal agent primarily used in the treatment of dermatophyte infections, particularly those affecting the skin and nails. It belongs to the class of imidazole derivatives and functions by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes, thereby disrupting their integrity and leading to cell death. Luliconazole is characterized by its broad-spectrum antifungal activity, making it effective against various fungi, including Trichophyton and Epidermophyton species. The substance is typically formulated as a topical cream, allowing for localized treatment with minimal systemic absorption. Its chemical structure includes a 1,2,4-triazole ring, which is essential for its antifungal properties. Luliconazole is generally well-tolerated, with a low incidence of side effects, making it a preferred choice for treating superficial fungal infections. Its efficacy and safety profile have been established through clinical studies, and it is available in several countries under various brand names.
Formula:C14H9Cl2N3S2
InChI:InChI=1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1
InChI key:InChIKey=YTAOBBFIOAEMLL-REQDGWNSSA-N
SMILES:ClC1=C(C=CC(Cl)=C1)[C@H]2S/C(=C(\C#N)/N3C=CN=C3)/SC2
Synonyms:- (2E)-2-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-ylacetonitrile
- (2E)-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene](1H-imidazol-1-yl)ethanenitrile
- (αE)-α-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile
- 1H-Imidazole-1-acetonitrile, α-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-, (αE)-
- 1H-Imidazole-1-acetonitrile, α-[4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-, [R-(E)]-
- 4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene-1-imidazolylacetonitrile
- Lulicon
- Nnd 502
- Luliconazole
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Luliconazole
CAS:Formula:C14H9Cl2N3S2Purity:>98.0%(HPLC)(N)Color and Shape:White to Orange to Green powder to crystalMolecular weight:354.27(R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-Dithiolan-2-Ylidene)-2-(1H-Imidazol-1-Yl)Acetonitrile
CAS:(R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-Dithiolan-2-Ylidene)-2-(1H-Imidazol-1-Yl)AcetonitrileFormula:C14H9Cl2N3S2Purity:97%Molecular weight:354.28Luliconazole
CAS:Formula:C14H9Cl2N3S2Purity:≥ 98.0%Color and Shape:White to off-white or pale yellow-orange powderMolecular weight:354.28(αE)-α-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile
CAS:Formula:C14H9Cl2N3S2Purity:95%Color and Shape:SolidMolecular weight:354.2774Luliconazole
CAS:Controlled ProductStability Light Sensitive
Applications Luliconazole is an azole antifungal drug.
References Uhida, K., et al.: J. Infect. Chemother., 10, 216 (2004); Niwano, ., et al.: Antimicro. Agents Chemother., 42, 967 (1998),Formula:C14H9Cl2N3S2Color and Shape:NeatMolecular weight:354.28Luliconazole
CAS:Luliconazole (NND 502) is an Azole Antifungal. The mechanism of action of luliconazole is as a Cytochrome P450 2C19 Inhibitor.Formula:C14H9Cl2N3S2Purity:98.27% - 99.83%Color and Shape:White SolidMolecular weight:354.277Luliconazole
CAS:Broad spectrum imidazole antifungalFormula:C14H9Cl2N3S2Purity:Min. 95%Color and Shape:Off-White To Yellow SolidMolecular weight:352.9615Luliconazole
CAS:(R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrileFormula:C14H9Cl2N3S2Purity:98%Molecular weight:354.28Luliconazole-d3
CAS:Controlled ProductFormula:C14D3H7Cl2N3S2Color and Shape:NeatMolecular weight:358.304
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