CAS 18776-12-0

3-CHLORO-1-PHENYL-1-PROPANOL

Description:

3-Chloro-1-phenyl-1-propanol is an organic compound characterized by its chlorinated structure, which includes a propanol backbone with a phenyl group and a chlorine atom attached to the third carbon. This compound typically appears as a colorless to pale yellow liquid and is known for its moderate solubility in water, influenced by the presence of the hydroxyl (-OH) group. The chlorine substituent can impart unique reactivity, making it a potential candidate for various chemical reactions, including nucleophilic substitutions. Its molecular structure suggests that it may exhibit both hydrophilic and hydrophobic properties, allowing it to interact with a range of solvents and biological systems. Additionally, 3-chloro-1-phenyl-1-propanol may have applications in organic synthesis, pharmaceuticals, or as an intermediate in the production of other chemical compounds. However, safety precautions should be taken when handling this substance, as chlorinated compounds can pose health risks and environmental concerns. Always refer to safety data sheets and regulatory guidelines for specific handling and disposal instructions.

Formula: C₉H₁₁ClO

InChI: InChI=1S/C9H11ClO/c10-7-6-9(11)8-4-2-1-3-5-8/h1-5,9,11H,6-7H2

InChI key: InChIKey=JZFUHAGLMZWKTF-UHFFFAOYSA-N

SMILES: C(CCCl)(O)C1=CC=CC=C1

Synonyms:

• 3-Chloro-1-Phenylpropanol
• Benzenemethanol, α-(2-chloroethyl)-
• Benzyl alcohol, α-(2-chloroethyl)-
• α-(2-Chloroethyl)benzenemethanol
• α-(2-Chloroethyl)benzyl alcohol
• 3-Chloro-1-phenyl-1-propanol
• rac 3-Chloro-1-phenylpropanol

3-Chloro-1-phenyl-1-propanol

CAS: 18776-12-0

Formula: C₉H₁₁ClO

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to lump

Molecular weight: 170.64

Ref: 3B-C2904

3-Chloro-1-Phenyl-1-Propanol

CAS: 18776-12-0

3-Chloro-1-Phenyl-1-Propanol

Formula: C₉H₁₁ClO

Purity: >98%

Color and Shape: Solid

Molecular weight: 170.64

Ref: 54-OR1010949

Atomoxetine Impurity 19

CAS: 18776-12-0

Formula: C₉H₁₁ClO

Molecular weight: 170.64

Ref: 4Z-A-2538

3-Chloro-1-phenylpropanol

CAS: 18776-12-0

Formula: C₉H₁₁ClO

Purity: 98%

Color and Shape: Solid

Molecular weight: 170.6360

Ref: IN-DA000OJR

rac 3-Chloro-1-phenylpropanol

Controlled Product

CAS: 18776-12-0

Applications An intermediate of racemic Atomoxetine.
References Hage, A., et al.: Biotechnol. Bioeng., 73, 69 (2001), La Regina, G., et al.: J. Med., Chem., 51, 3841 (2008),

Formula: C₉H₁₁ClO

Color and Shape: Neat

Molecular weight: 170.64

Ref: TR-C379650

3-Chloro-1-phenylpropan-1-ol

CAS: 18776-12-0

Formula: C₉H₁₁ClO

Molecular weight: 170.63

Ref: BE-RMCA314032

3-Chloro-1-phenyl-propanol

CAS: 18776-12-0

Formula: C₉H₁₁ClO

Purity: 98%

Color and Shape: Solid

Molecular weight: 170.64

Ref: 10-F049245

3-Chloro-1-phenyl-propanol

CAS: 18776-12-0

3-Chloro-1-phenylpropan-1-ol

Formula: C₉H₁₁ClO

Purity: 97%

Molecular weight: 170.64

Ref: IN-DG85546

Fluoxetine impurity 5

CAS: 18776-12-0

Formula: C₉H₁₁ClO

Molecular weight: 170.6

Ref: ST-EA-CP-F19010

3-Chloro-1-phenyl-1-propanol

CAS: 18776-12-0

Formula: C₉H₁₁ClO

Molecular weight: 170.64

Ref: ST-EA-CP-A30031

rac 3-chloro-1-phenylpropanol

CAS: 18776-12-0

Racemic 3-chloro-1-phenylpropanol is an antidepressant drug that belongs to the class of phenylpropanoids. Racemic 3-chloro-1-phenylpropanol is a chiral compound with two enantiomers, which can be differentiated by their optical rotation or by their boiling point. Racemic 3-chloro-1-phenylpropanol has been synthesized from fatty acids and reacts with an aqueous solution of sodium hydroxide at room temperature. The optimum concentration for racemic 3-chloro-1-phenylpropanol isomers was found to be 0.9 M, while the reaction solution should be cooled in order to prevent decomposition of the product. Racemic 3-chloro-1-phenylpropanol has been shown to have antidepressant activity in animal tests and can be used in the treatment of depression. Racemic 3 - chloro - 1 - phenylpropan

Formula: C₉H₁₁ClO

Purity: Min. 95%

Molecular weight: 170.64 g/mol

Ref: 3D-FR27446