CAS 188062-50-2
:Abacavir sulfate
Description:
Abacavir sulfate is an antiretroviral medication primarily used in the treatment of HIV infection. It is a nucleoside reverse transcriptase inhibitor (NRTI) that works by interfering with the viral replication process. The compound is characterized by its chemical structure, which includes a bicyclic core and a sulfate moiety, contributing to its pharmacological properties. Abacavir is known for its oral bioavailability and is often administered in combination with other antiretroviral agents to enhance efficacy and reduce the risk of resistance. It is important to note that abacavir can cause hypersensitivity reactions in some individuals, necessitating genetic testing for the HLA-B*5701 allele prior to initiation of therapy. The substance is typically supplied as a sulfate salt to improve solubility and stability. In terms of physical properties, abacavir sulfate is a white to off-white powder, and it is soluble in water, making it suitable for formulation in various dosage forms. Overall, abacavir sulfate plays a crucial role in modern HIV treatment regimens.
Formula:C14H18N6OH2O4S
InChI:InChI=1S/C14H18N6O.H2O4S/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t8-,10+;/m1./s1
InChI key:InChIKey=MBFKCGGQTYQTLR-SCYNACPDSA-N
SMILES:N(C1=C2C(N(C=N2)[C@@H]3C[C@H](CO)C=C3)=NC(N)=N1)C4CC4.S(=O)(=O)(O)O
Synonyms:- (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol sulfate
- 1592U89 sulfate
- 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-, sulfate (2:1)
- 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-, sulfate (2:1) (salt)
- 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S-cis)-, sulfate (2:1) (salt)
- ABC sulfate
- Abacavir Sulfale
- Abacavir hemisulfate
- Abacavir sulphate
- Abamune
- Abavir
- Drg 0257
- Ziagen
- See more synonyms
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Found 20 products.
ABACAVIR SULFATE FOR SYSTEM SUITABILITY RS
CAS:ABACAVIR SULFATE FOR SYSTEM SUITABILITY RSFormula:C14H20N6O5SColor and Shape:PowderMolecular weight:384.4108ABACAVIR SULFATE CRS
CAS:ABACAVIR SULFATE CRSFormula:C14H20N6O5SColor and Shape:PowderMolecular weight:384.4108Abacavir sulfate
CAS:Abacavir sulfateFormula:C28H38N12O6SPurity:99.7%Color and Shape:Off WhiteMolecular weight:670.2758ABACAVIR FOR SYSTEM SUITABILITY CRS
CAS:ABACAVIR FOR SYSTEM SUITABILITY CRSFormula:C14H20N6O5SColor and Shape:PowderMolecular weight:384.4108ABACAVIR SULFATE RS
CAS:ABACAVIR SULFATE RSFormula:C14H20N6O5SColor and Shape:PowderMolecular weight:384.4108ABACAVIR FOR PEAK IDENTIFICATION CRS
CAS:ABACAVIR FOR PEAK IDENTIFICATION CRSFormula:C14H20N6O5SColor and Shape:PowderMolecular weight:384.4108Abacavir Sulfate Racemic (4-[2-amino-6-(cyclopropylamino)-9H-purin-9yl]-2-cyclopentene-1-methanol sulfate (2:1))
CAS:Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, nesoiFormula:(C14H18N6O)2·H2SO4Color and Shape:Off-White PowderMolecular weight:670.2758Abacavir Sulfate
CAS:Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structureFormula:(C14H18N6O)2·H2SO4Color and Shape:White Off-White Crystalline PowderMolecular weight:670.27582-CYCLOPENTENE-1-METHANOL, 4-[2-AMINO-6-(CYCLOPROPYLAMINO)-9H-PURIN-9-YL]-, (1S,4R)-, SULFATE (2:1)
CAS:Formula:C14H20N6O5SPurity:99%Color and Shape:SolidMolecular weight:384.4108Abacavir sulfate
CAS:Formula:C14H18N6O·5(H2SO4)Purity:≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:335.37((1S,4R)-4-(2-Amino-6-(Cyclopropylamino)-9H-Purin-9-yl)Cyclopent-2-en-1-yl)Methanol Hemisulfate
CAS:((1S,4R)-4-(2-Amino-6-(Cyclopropylamino)-9H-Purin-9-yl)Cyclopent-2-en-1-yl)Methanol HemisulfatePurity:98%Molecular weight:670.74g/molAbacavir Sulfate
CAS:Formula:C28H36N12O2·H2O4SPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:670.75Abacavir Sulfate
CAS:Controlled ProductFormula:C14H18N6O·H2O4SColor and Shape:NeatMolecular weight:670.74Abacavir sulfate
CAS:Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activityFormula:C14H18N6OH2O4SPurity:99.79% - 99.85%Color and Shape:White To Off-White SolidMolecular weight:335.38Abacavir sulfate
CAS:Controlled Product<p>Impurity Abacavir - In House Impurity<br>Applications Abacavir Sulfate (Abacavir - In House Impurity) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br>References (1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)<br></p>Formula:C14H18N6O·H2O4SColor and Shape:Off WhiteMolecular weight:670.74Abacavir sulfate
CAS:<p>Anti-viral; reverse transcriptase inhibitor</p>Formula:C14H18N6OH2SO4Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:670.75 g/molAbacavir sulfate - Bio-X ™
CAS:<p>Abacavir sulfate is an antiviral drug that belongs to the class of HIV protease inhibitors. It is used in combination with other antiretroviral drugs to treat HIV-1 infection. Abacavir sulfate inhibits viral replication by blocking the activity of HIV-1 protease, which is necessary for the production of new virus particles.<br>Abacavir sulfate is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>Formula:C14H18N6OH2SO4Purity:Min. 98 Area-%Color and Shape:SolidMolecular weight:670.75 g/molrac-Abacavir Sulfate
CAS:Controlled ProductFormula:C14H18N6O·H2SO4Color and Shape:NeatMolecular weight:670.743
![Abacavir Sulfate Racemic (4-[2-amino-6-(cyclopropylamino)-9H-purin-9yl]-2-cyclopentene-1-methanol …](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F45%2Fthumb%2F1000419.jpg&w=3840&q=75)
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