CAS 188062-50-2: Abacavir sulfate

Description: Abacavir sulfate is an antiretroviral medication primarily used in the treatment of HIV infection. It is a nucleoside reverse transcriptase inhibitor (NRTI) that works by interfering with the viral replication process. The compound is characterized by its chemical structure, which includes a bicyclic core and a sulfate moiety, contributing to its pharmacological properties. Abacavir is known for its oral bioavailability and is often administered in combination with other antiretroviral agents to enhance efficacy and reduce the risk of resistance. It is important to note that abacavir can cause hypersensitivity reactions in some individuals, necessitating genetic testing for the HLA-B*5701 allele prior to initiation of therapy. The substance is typically supplied as a sulfate salt to improve solubility and stability. In terms of physical properties, abacavir sulfate is a white to off-white powder, and it is soluble in water, making it suitable for formulation in various dosage forms. Overall, abacavir sulfate plays a crucial role in modern HIV treatment regimens.

Formula: C₁₄H₁₈N₆OH₂O₄S

InChI: InChI=1S/C14H18N6O.H2O4S/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t8-,10+;/m1./s1

InChI key: InChIKey=MBFKCGGQTYQTLR-SCYNACPDSA-N

SMILES: O=S(=O)(O)O.OCC1C=CC(N2C=NC=3C(=NC(=NC32)N)NC4CC4)C1

Synonyms:

• (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol sulfate
• 1592U89 sulfate
• 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-, sulfate (2:1)
• 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-, sulfate (2:1) (salt)
• 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S-cis)-, sulfate (2:1) (salt)
• ABC sulfate
• Abacavir Sulfale
• Abacavir hemisulfate
• Abacavir sulphate
• Abamune
• Abavir
• Drg 0257
• Ziagen
• Abacavir sulfate

Abacavir sulfate for system suitability RS

CAS: 188062-50-2

• Formula: C₁₄H₂₀N₆O₅S
• Color and Shape: Powder
• Molecular weight: 384.4108

Abacavir sulfate CRS

CAS: 188062-50-2

• Formula: C₁₄H₂₀N₆O₅S
• Color and Shape: Powder
• Molecular weight: 384.4108

Abacavir impurity standard

CAS: 188062-50-2

• Color and Shape: Off-White

Abacavir sulfate

CAS: 188062-50-2

• Formula: C₂₈H₃₈N₁₂O₆S
• Purity: 99.7%
• Color and Shape: Off White
• Molecular weight: 670.2758

Abacavir sulfate RS

CAS: 188062-50-2

• Formula: C₁₄H₂₀N₆O₅S
• Color and Shape: Powder
• Molecular weight: 384.4108

Abacavir for system suitability CRS

CAS: 188062-50-2

• Formula: C₁₄H₂₀N₆O₅S
• Color and Shape: Powder
• Molecular weight: 384.4108

Abacavir for peak identification CRS

CAS: 188062-50-2

• Formula: C₁₄H₂₀N₆O₅S
• Color and Shape: Powder
• Molecular weight: 384.4108

Abacavir Sulfate Racemic (4-[2-amino-6-(cyclopropylamino)-9H-purin-9yl]-2-cyclopentene-1-methanol sulfate (2:1))

CAS: 188062-50-2

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, …

• Formula: (C₁₄H₁₈N₆O)₂·H₂SO₄
• Color and Shape: Off-White Powder
• Molecular weight: 670.2758

Abacavir Sulfate

CAS: 188062-50-2

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

• Formula: (C₁₄H₁₈N₆O)₂·H₂SO₄
• Color and Shape: White Off-White Crystalline Powder
• Molecular weight: 670.2758

2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-, sulfate (2:1)

CAS: 188062-50-2

• Formula: C₂₈H₃₈N₁₂O₆S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 670.7431

((1S,4R)-4-(2-Amino-6-(Cyclopropylamino)-9H-Purin-9-yl)Cyclopent-2-en-1-yl)Methanol Hemisulfate

CAS: 188062-50-2

• Purity: 98%
• Molecular weight: 670.74g/mol

Abacavir sulfate

CAS: 188062-50-2

• Formula: C₁₄H₁₈N₆O·5(H₂SO₄)
• Purity: ≥ 98.0%
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 335.37

Abacavir Sulfate

CAS: 188062-50-2

• Formula: C₂₈H₃₆N₁₂O₂·H₂O₄S
• Purity: >95.0%(T)(HPLC)
• Color and Shape: White to Light yellow to Light orange powder to crystal
• Molecular weight: 670.75

Abacavir sulfate, 99 %

CAS: 188062-50-2

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂₈H₃₈N₁₂O₆S
• Color and Shape: Crystalline powder, White to light beige
• Molecular weight: 670.75

Abacavir Sulfate

CAS: 188062-50-2

• Formula: C₁₄H₁₈N₆O·H₂O₄S
• Color and Shape: Neat
• Molecular weight: 670.74

Abacavir sulfate

CAS: 188062-50-2

Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity

• Formula: C₁₄H₁₈N₆OH₂O₄S
• Purity: 100% - 99.85%
• Color and Shape: White To Off-White Solid
• Molecular weight: 335.38

Abacavir sulfate

CAS: 188062-50-2

Impurity Abacavir - In House Impurity Applications Abacavir Sulfate (Abacavir - In House Impurity) is …

• Formula: C₁₄H₁₈N₆O·H₂O₄S
• Color and Shape: Off White
• Molecular weight: 670.74

Abacavir sulfate

CAS: 188062-50-2

Anti-viral; reverse transcriptase inhibitor

• Formula: C₁₄H₁₈N₆OH₂SO₄
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 670.75 g/mol

Abacavir sulfate - Bio-X ™

CAS: 188062-50-2

Abacavir sulfate is an antiviral drug that belongs to the class of HIV protease inhibitors. …

• Formula: C₁₄H₁₈N₆OH₂SO₄
• Purity: Min. 98 Area-%
• Color and Shape: Solid
• Molecular weight: 670.75 g/mol

rac-Abacavir Sulfate

CAS: 136470-79-6 188062-50-2

• Formula: C₁₄H₁₈N₆O·H₂SO₄
• Color and Shape: Neat
• Molecular weight: 670.743