CAS 18818-64-9

Temazepam acetate

Description:

Temazepam acetate is a derivative of temazepam, which is a benzodiazepine commonly used for its sedative and anxiolytic properties. As a chemical substance, it exhibits characteristics typical of benzodiazepines, including its ability to enhance the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased sedation and relaxation. Temazepam acetate is typically administered in the form of its acetate ester, which may influence its pharmacokinetics and bioavailability. The compound is generally characterized by its moderate lipophilicity, allowing it to cross the blood-brain barrier effectively. It is often used in the treatment of insomnia and other sleep disorders due to its hypnotic effects. However, like other benzodiazepines, it carries risks of dependence, tolerance, and withdrawal symptoms with prolonged use. Safety and efficacy are paramount, and it is usually prescribed for short-term use under medical supervision. As with all medications, potential side effects and interactions with other substances should be carefully considered.

Formula: C₁₈H₁₅ClN₂O₃

InChI: InChI=1/C18H15ClN2O3/c1-11(22)24-17-18(23)21(2)15-9-8-13(19)10-14(15)16(20-17)12-6-4-3-5-7-12/h3-10,17H,1-2H3

InChI key: InChIKey=PTWWAHZQIATUFG-UHFFFAOYSA-N

SMILES: O(C(C)=O)C1N=C(C=2C(N(C)C1=O)=CC=C(Cl)C2)C3=CC=CC=C3

Synonyms:

• 2H-1,4-Benzodiazepin-2-one, 3-(acetyloxy)-7-chloro-1,3-dihydro-1-methyl-5-phenyl-
• 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-, acetate
• 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-, acetate (ester)
• 3-(Acetyloxy)-7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
• 3-Acetoxydiazepam
• 7-chloro-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl acetate
• Temazepam acetate
• 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2-oxo-2H-1,4-benzodiazepin-3-yl acetate
• Einecs 242-597-2
• PTWWAHZQIATUFG-UHFFFAOYSA-N
• (3RS)-7-Chloro-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl acetate

Temazepam Acetate

Controlled Product

CAS: 18818-64-9

Applications Temazepam Acetate is an impurity of temazepam (T017200), which is a pharmacologically active metabolite of Diazepam. It is used as a sedative and hypnotic drug.
References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),

Formula: C₁₈H₁₅ClN₂O₃

Color and Shape: Neat

Molecular weight: 342.78

Ref: TR-T017205

Temazepam EP impurity C

CAS: 18818-64-9

Formula: C₁₈H₁₅ClN₂O₃

Molecular weight: 342.8

Ref: ST-EA-CP-T41003