CAS 1883300-48-8

Formula: C18H20F3N7O

InChI: InChI=1S/C18H20F3N7O/c1-9-12-7-28(8-17(9,12)26-15(29)11-3-18(11,20)21)14-13(19)5-22-16(25-14)24-10-4-23-27(2)6-10/h4-6,9,11-12H,3,7-8H2,1-2H3,(H,26,29)(H,22,24,25)/t9-,11+,12+,17+/m1/s1

InChI key: VFTQZQGHFFDMQS-RSNHQYPWSA-N

SMILES: C[C@@H]1[C@H]2[C@@]1(CN(C2)C3=NC(=NC=C3F)NC4=CN(N=C4)C)NC(=O)[C@@H]5CC5(F)F

JAK1/TYK2-IN-1

CAS: 1883300-48-8

JAK1/TYK2-IN-1 is a dual inhibitor of TYK2 and JAK1 ( IC 50 = 29 and 41 nM respectively).

Formula: C₁₈H₂₀F₃N₇O

Color and Shape: Solid

Molecular weight: 407.401

Ref: TM-T39314