CAS 1887069-10-4

Formula: C22H20ClN5O3S

InChI: InChI=1S/C22H20ClN5O3S/c1-3-30-10-12-9-25-22(23)28-21(12)31-16-7-4-13-14(27-16)5-6-15-17(13)18-19(32-15)20(29)26-11(2)8-24-18/h4-7,9,11,24H,3,8,10H2,1-2H3,(H,26,29)/t11-/m1/s1

InChI key: PYOQIOLRFIRRSO-LLVKDONJSA-N

SMILES: CCOCC1=CN=C(N=C1OC2=NC3=C(C=C2)C4=C(C=C3)SC5=C4NC[C@H](NC5=O)C)Cl

CC-99677

CAS: 1887069-10-4

CC-99677

Formula: C₂₂H₂₀ClN₅O₃S

Purity: ≥98%

Molecular weight: 469.94

Ref: 54-BUP00785

CC-99677

CAS: 1887069-10-4

CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.

Formula: C₂₂H₂₀ClN₅O₃S

Purity: 99.59%

Color and Shape: Solid

Molecular weight: 469.944

Ref: TM-T39321

(R)-3-((2-Chloro-5-(ethoxymethyl)pyrimidin-4-yl)oxy)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one

CAS: 1887069-10-4

Formula: C₂₂H₂₀ClN₅O₃S

Purity: 97%

Molecular weight: 469.9439

Ref: IN-DA027JFK

Gamcemetinib

CAS: 1887069-10-4

(R)-3-((2-Chloro-5-(ethoxymethyl)pyrimidin-4-yl)oxy)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one

Formula: C₂₂H₂₀ClN₅O₃S

Purity: 97%

Molecular weight: 469.94

Ref: IN-DG01420611