CAS 189224-26-8

Ozagrel sodium

Description:

Ozagrel sodium is a synthetic compound primarily used as a thromboxane A2 receptor antagonist, which plays a role in inhibiting platelet aggregation and promoting vasodilation. It is classified as a non-steroidal anti-inflammatory drug (NSAID) and is often utilized in the treatment of conditions related to cardiovascular health, particularly in managing acute ischemic stroke and other thromboembolic disorders. The substance is characterized by its ability to selectively inhibit the action of thromboxane A2, a potent vasoconstrictor and platelet aggregator, thereby contributing to improved blood flow and reduced clot formation. Ozagrel sodium is typically administered intravenously and is known for its relatively rapid onset of action. Its pharmacokinetics involve metabolism primarily in the liver, with excretion occurring through the kidneys. As with any medication, potential side effects may include bleeding complications, gastrointestinal disturbances, and allergic reactions. Overall, Ozagrel sodium represents a significant therapeutic option in the management of thrombotic conditions, highlighting the importance of targeted pharmacological interventions in cardiovascular medicine.

Formula: C₁₃H₁₂N₂NaO₂

InChI: InChI=1/C13H12N2O2.Na/c16-13(17)6-5-11-1-3-12(4-2-11)9-15-8-7-14-10-15;/h1-8,10H,9H2,(H,16,17);/q;+1/b6-5+;

SMILES: c1cc(ccc1C=CC(=O)O)Cn1ccnc1.[Na]

Synonyms:

• (2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid sodium salt
• sodium (2E)-3-[4-(1H-imidazol-1-ylmethyl)phenyl]prop-2-enoate
• 2-propenoic acid, 3-[4-(1H-imidazol-1-ylmethyl)phenyl]-, sodium salt, (2E)- (1:1)

Ozagrel Hydrochloride

CAS: 189224-26-8, 78712-43-3, 82571-53-7

Formula: C₁₃H₁₂N₂O₂·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 264.71

Ref: 3B-O0419

2-Propenoic acid, 3-[4-(1H-imidazol-1-ylmethyl)phenyl]-, sodium salt,(2E)-

CAS: 189224-26-8

Formula: C₁₃H₁₁N₂NaO₂

Purity: 95%

Molecular weight: 250.2284

Ref: IN-DA00AOGO

Ozagrel Sodium

CAS: 189224-26-8

Ozagrel Sodium is a thromboxane A2 synthase inhibitor. It is used to treat cerebrovascular diseases.

Formula: C₁₃H₁₂N₂NaO₂

Purity: 98%

Color and Shape: White Or Off-White Crystalline Powder

Molecular weight: 251.24

Ref: TM-T6236L

Ozagrel Sodium

CAS: 189224-26-8

Formula: C₁₃H₁₁N₂NaO₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 250.23

Ref: 3B-O0660

Ozagrel Sodium RS

CAS: 189224-26-8

Color and Shape: White

Ref: 2K-1034000021

Ozagrel sodium

CAS: 189224-26-8

Ozagrel is an experimental drug that belongs to the class of ester hydrochlorides. It has been shown to have chemical properties similar to those of dinucleotide phosphate (NDP) and can be used as a synchronous fluorescence probe for NDP. Ozagrel is an inhibitor of synthetase, which is the enzyme that catalyzes the conversion of glucose into NDP. The combination therapy group showed a statistically significant improvement in bowel disease when treated with ozagrel, compared with the control group. This drug also has cerebral protective effects and may prove useful in combination therapy for cerebral diseases such as stroke or Alzheimer's Disease.

Formula: C₁₃H₁₂N₂O₂•Na

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 251.24 g/mol

Ref: 3D-FO65119