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CAS 189224-26-8

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Ozagrel sodium

Description:
Ozagrel sodium is a synthetic compound primarily used as a thromboxane A2 receptor antagonist, which plays a role in inhibiting platelet aggregation and promoting vasodilation. It is classified as a non-steroidal anti-inflammatory drug (NSAID) and is often utilized in the treatment of conditions related to cardiovascular health, particularly in managing acute ischemic stroke and other thromboembolic disorders. The substance is characterized by its ability to selectively inhibit the action of thromboxane A2, a potent vasoconstrictor and platelet aggregator, thereby contributing to improved blood flow and reduced clot formation. Ozagrel sodium is typically administered intravenously and is known for its relatively rapid onset of action. Its pharmacokinetics involve metabolism primarily in the liver, with excretion occurring through the kidneys. As with any medication, potential side effects may include bleeding complications, gastrointestinal disturbances, and allergic reactions. Overall, Ozagrel sodium represents a significant therapeutic option in the management of thrombotic conditions, highlighting the importance of targeted pharmacological interventions in cardiovascular medicine.
Formula:C13H12N2NaO2
InChI:InChI=1/C13H12N2O2.Na/c16-13(17)6-5-11-1-3-12(4-2-11)9-15-8-7-14-10-15;/h1-8,10H,9H2,(H,16,17);/q;+1/b6-5+;
SMILES:c1cc(ccc1C=CC(=O)O)Cn1ccnc1.[Na]
Synonyms:
  • (2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid sodium salt
  • sodium (2E)-3-[4-(1H-imidazol-1-ylmethyl)phenyl]prop-2-enoate
  • 2-propenoic acid, 3-[4-(1H-imidazol-1-ylmethyl)phenyl]-, sodium salt, (2E)- (1:1)
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