CAS 191217-81-9: Pramipexole dihydrochloride monohydrate
Description:Pramipexole dihydrochloride monohydrate is a medication primarily used in the treatment of Parkinson's disease and restless legs syndrome. It acts as a selective agonist for dopamine D2 and D3 receptors, which helps to alleviate symptoms associated with these conditions. The substance is a white to off-white crystalline powder, soluble in water, and has a molecular formula that includes both hydrochloride and monohydrate components, indicating the presence of water molecules in its crystalline structure. Its pharmacological profile allows it to enhance dopaminergic activity in the brain, which is crucial for motor control. The compound is typically administered orally and is known for its relatively favorable side effect profile compared to other dopaminergic agents. Additionally, pramipexole has a half-life that supports once or twice daily dosing, making it convenient for patients. As with any medication, it is important to monitor for potential side effects, including nausea, dizziness, and sleep disturbances, particularly during the initial stages of treatment or when adjusting dosages.
Formula:C10H17N3S·2ClH·H2O
InChI:InChI=1S/C10H17N3S.2ClH.H2O/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8;;;/h7,12H,2-6H2,1H3,(H2,11,13);2*1H;1H2/t7-;;;/m0.../s1
InChI key:InChIKey=APVQOOKHDZVJEX-QTPLPEIMSA-N
SMILES:Cl.O.N1=C(SC2=C1CCC(NCCC)C2)N
- Synonyms:
- (6S)-N'-Propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine hydrate dihydrochloride
- (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride monohydrate
- 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N<sup>6</sup>-propyl-, dihydrochloride, monohydrate, (6S)-
- 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N<sup>6</sup>-propyl-, dihydrochloride, monohydrate, (S)-
- 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N<sup>6</sup>-propyl-, hydrochloride, hydrate (1:2:1), (6S)-
- BI-sifrol
- Daquiran
- Mirapex
- Mirapexin
- N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine dihydrochloride hydrate
- See more synonyms
- Oprymea
- Pramipexole 2HCL monohydrate
- Pramipexole hydrochloride hydrate
- Sifrol
- Pramipexole dihydrochloride monohydrate
- 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, dihydrochloride, monohydrate, (S)-
- 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, hydrochloride, hydrate (1:2:1), (6S)-
- 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, dihydrochloride, monohydrate, (6S)-
