![(3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one](https://static.cymitquimica.com/cas-image/thumb-webp/336939-3r-4s-1-4-fluorophenyl-3-3-4-fluorophenyl-3-oxopropyl-4-4-hydroxyphenyl-azetidin-2-one.webp)
CAS 191330-56-0
:(3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one
Description:
The chemical substance known as "(3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one," with the CAS number 191330-56-0, is a synthetic organic compound characterized by its azetidinone core structure. This compound features multiple functional groups, including a fluorophenyl moiety and a hydroxyphenyl group, which contribute to its potential biological activity. The presence of the fluorine atom enhances lipophilicity and may influence the compound's interaction with biological targets. The stereochemistry indicated by the (3R,4S) configuration suggests specific spatial arrangements of atoms that can significantly affect the compound's pharmacological properties. Such compounds are often studied for their potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting various diseases. The intricate structure and functional groups may also suggest reactivity patterns that could be explored in synthetic chemistry or drug design. Overall, this compound exemplifies the complexity and diversity found in organic molecules used in therapeutic contexts.
Formula:C24H19F2NO3
InChI:InChI=1S/C24H19F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21,23,28H,13-14H2/t21-,23-/m1/s1
InChI key:InChIKey=UEPZDXMEEKCJSP-FYYLOGMGSA-N
SMILES:C(CC(=O)C1=CC=C(F)C=C1)[C@@H]2[C@H](N(C2=O)C3=CC=C(F)C=C3)C4=CC=C(O)C=C4
Synonyms:- (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone
- (3R,4S)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one
- 2-Azetidinone, 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-, (3R,4S)-
- 2-Azetidinone, 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-, (3R-trans)-
- Ezetimibe Ketone
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Ezetimibe Ketone
CAS:Lactams, nesoiFormula:C24H19F2NO3Color and Shape:White SolidMolecular weight:407.1333(3R,4S)-1-(4-Fluorophenyl)-3-(3-(4-Fluorophenyl)-3-Oxopropyl)-4-(4-Hydroxyphenyl)Azetidin-2-One
CAS:Formula:C24H19F2NO3Purity:98%Color and Shape:SolidMolecular weight:407.4094Ezetimibe Ketone
CAS:Controlled ProductImpurity Ezetimibe Ketone (USP)
Applications Phase-I metabolite of Ezetimibe (E975000).
References Shah, V., et al: J. Pharm. Sci., 17, 1551 (2000), Van Heek, M., et al.: Br. J. Pharmacol., 134, 409 (2001), Watts, G., et al.: Clin. Sci.,103, 595 (2002), Ghosal, A., et al.: Drug Metab. Dispos., 32, 314 (2004), Sistla, R., et al.: J. Pharm. Biomed. Anal., 39, 517 (2005),Formula:C24H19F2NO3Color and Shape:NeatMolecular weight:407.41Ezetimibe ketone
CAS:(3R,4S)-1-(4-Fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)-4-(4-hydroxyphenyl)azetidin-2-oneFormula:C24H19F2NO3Purity:98%Molecular weight:407.41Ezetimibe ketone
CAS:Ezetimibe ketone (EZM-K) exhibits antioxidant activity and alleviates H2O2-induced NRK-52E cell apoptosis by upregulating Nrf2 and HO-1 levels.Formula:C24H19F2NO3Purity:99.32%Color and Shape:Yellow SolidMolecular weight:407.4094(3R,4S)-1-(4-FLUOROPHENYL)-3-(3-(4-FLUOROPHENYL)-3-OXOPROPYL)-4-(4-HYDROXYPHENYL)AZETIDIN-2-ONE
CAS:Purity:98%Molecular weight:407.4169922
