CAS 192704-56-6

11α-Hydroxymexrenone

Description:

11α-Hydroxymexrenone is a synthetic steroid compound that belongs to the class of glucocorticoids, which are known for their anti-inflammatory and immunosuppressive properties. It is characterized by its hydroxyl group at the 11α position, which distinguishes it from other related steroid compounds. The molecular structure of 11α-Hydroxymexrenone contributes to its biological activity, influencing its interaction with glucocorticoid receptors. This compound is often studied for its potential therapeutic applications, particularly in conditions requiring modulation of the immune response or inflammation. Its pharmacological profile may include effects on metabolism, electrolyte balance, and various physiological processes. As with many glucocorticoids, the use of 11α-Hydroxymexrenone may be associated with a range of side effects, necessitating careful consideration in clinical settings. Overall, its unique structural features and biological activities make it a subject of interest in medicinal chemistry and pharmacology.

Formula: C₂₄H₃₂O₆

InChI: InChI=1S/C24H32O6/c1-22-7-4-14(25)10-13(22)11-15(21(28)29-3)19-16-5-8-24(9-6-18(27)30-24)23(16,2)12-17(26)20(19)22/h10,15-17,19-20,26H,4-9,11-12H2,1-3H3/t15-,16+,17-,19+,20+,22+,23+,24-/m1/s1

InChI key: InChIKey=ZYDNRZOTRVTMRC-IIYDDONESA-N

SMILES: C(OC)(=O)[C@H]1[C@]2([C@]3([C@@](C)([C@@]4(CC3)CCC(=O)O4)C[C@@H](O)[C@@]2([C@]5(C)C(C1)=CC(=O)CC5)[H])[H])[H]

Synonyms:

• 11-Alpha-Hydroxy-7-Alpha-(Methoxycarbonyl)-3-Oxopregn-4-Ene-21,17-Alpha-Carbolactone
• 11α,17β-Dihydroxypregn-4-en-3-one 7α,21-dicarboxylic acid γ-lactone methyl ester
• 11α-Hydroxy-7α-(methoxycarbonyl)-3-oxopregn-4-ene-21,17α-carbolactone
• 11α-Hydroxymexrenone
• Pregn-4-ene-7,21-dicarboxylic acid, 11,17-dihydroxy-3-oxo-, γ-lactone, methyl ester, (7α,11α,17α)-
• 11α-Hydroxymexrenone(A2)
• 11α-Hydroxy Mexrenone
• Eplerenone 11α-Hydroxy Analog
• 11α-Hydroxy canrenone methyl ester
• Eplerenone intermediate A2
• Eplerenone 11-alpha-Hydroxy Analog
• 11α-HydroxEplerenone Impurity
• 11-Alpha-Hydroxy canrenone methyl ester
• 11-a-Hydroxy canrenone methyl ester
• 11alpha-Hydroxymexrenone
• (7α,11α,17α)-11,17-Dihydroxy-3-oxopregn-4-ene-7,21-dicarboxylic Acid γ-Lactone Methyl Ester
• Pregn-4-ene-7,21-dicarboxylicacid, 11,17-dihydroxy-3-oxo-, g-lactone, methyl ester, (7a,11a,17a)-
• TIANFU-CHEM 11-a-Hydroxy canrenone methyl ester
• 11a-Hydroxy Mexrenone

11-A-Hydroxy Canrenone Methyl Ester

CAS: 192704-56-6

11-A-Hydroxy Canrenone Methyl Ester

Formula: C₂₄H₃₂O₆

Purity: 98%

Molecular weight: 416.51

Ref: 54-OR1030401

11α-Hydroxy-7α-(methoxycarbonyl)-3-oxopregn-4-ene-21,17α-carbolactone

CAS: 192704-56-6

Formula: C₂₄H₃₂O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 416.5073

Ref: IN-DA002G89

Eplerenone Impurity 2

CAS: 192704-56-6

Formula: C₂₄H₃₂O₆

Color and Shape: Off-White Solid

Molecular weight: 416.51

Ref: 4Z-E-1315

11-A-Hydroxy canrenone methyl ester

CAS: 192704-56-6

Formula: C₂₄H₃₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 416.514

Ref: 10-F093751

11α-Hydroxy Mexrenone

Controlled Product

CAS: 192704-56-6

Applications 11α-Hydroxy Mexrenone is an intermediate used in the chemobiological synthesis of Eplerenone (E588775), a cardiovascular drug.
References Boeren, S., et al.: Biotech. Bioeng., 29, 305 (1987), Anon., et al.: Drugs Future, 25, 516 (2000), McMahon, E., et al.: Curr. Opin Pharmacol., 1, 190 (2001),

Formula: C₂₄H₃₂O₆

Color and Shape: Neat

Molecular weight: 416.51

Ref: TR-H948140